Results 51 to 60 of about 808,349 (313)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Estudios Geologicos, 1998 La formación de plagioclasa sódica (Pl) y de vidrio en las peridotitas de Saghro (Anti-Atlas marroquí) y de La Palma (Islas Canarias) se puede explicar como resultado de un proceso de metasomatismo y de fusión parcial de climpyroxeno (Cpx) y espinela ...
A. Ibhi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Sentidos e significados da trajetória laboral de uma pessoa com deficiência no mundo do trabalho
Revista Trabalho, Política e SociedadeA pesquisa visa compreender o processo de inclusão no mercado de trabalho a partir da narrativa dos sentidos e significados da trajetória laboral de uma pessoa com deficiência. Na perspectiva da Psicologia Social dodo Trabalho assumem-se os conceitos de
Carolina Moreira de Pinho Tavares +2 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Northern Territory of South Australia [cartographic material]
, 1886 Map of the Northern Territory showing places named after British Prime Ministers and parliamentarians. Relief shown by hachures.; Prime meridian: Greenwich.; From: Picturesque atlas of Australasia.
Picturesque Atlas Publishing Company.
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Educación XX1, 2012 Puesto que la Formación Inicial Docente (FID) ha sido, en este último tiempo, parte de la agenda nacional del Ministerio de Educación de Chile, este estudio tiene como objetivo comprender los patrones de comunicación establecidos entre un grupo ...
Claudio Díaz Larenas +1 more
doaj +1 more source
, 1994 Die Analyse eines Fremdsprachentextes wird in der linguistischen Textanalyse seit jeher mit den klassischen Arbeitsmitteln durchgeführt - Buch, Papier und Bleistift. Im Rahmen eines Hauptseminars an der TU Berlin entstand die Idee, die Analyse eines Fremdsprachentextes einmal ganz anders durchzuführen: Unter Zuhilfenahme von Atlas/ti sollte auf die ...
Rauschendorf, Mimi K., Plate, Rebekka
openaire +1 more source