Results 111 to 120 of about 634,659 (335)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway

open access: yesCancer Management and Research, 2020
Rui Zhang,1,* Dan Han,2,* Lu Li,2,* Wenguang Luo,3 Jing Liu,4 Liting Qian3 1Department of Oncology, QingPu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai 201799, People’s Republic of China; 2Division of Life Science and ...
Zhang R   +5 more
doaj  

Supplementary Tables (S1-S5) from An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling

open access: gold, 2023
Geyan Wu   +8 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Modelling flexible thrust performance for trajectory prediction applications in ATM [PDF]

open access: yes, 2016
Reduced thrust operations are of widespread use nowadays due to their inherit benefits for engine conservation. Therefore, in order to enable realistic simulation of air traffic management (ATM) scenarios for purposes such as
Casado, Enrique   +7 more
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Experiments for analysis of video transmission via ATM

open access: yesJournal of Computer Science and Technology, 2002
A large quantity of data of different types and priorities pass through on high-speed networks. A relevant part of these data, like continuous media (audio, video, and so), need a control of its Quality of Service (QoS).
Mauricio Pissioli   +2 more
doaj  

PD-L1 and immune infiltrates are differentially expressed in distinct subgroups of gastric cancer

open access: yesOncoImmunology, 2019
This study investigates the association of PD-L1 expression and immune cell infiltrates and their impact on clinical outcome, in addition to their overlap with microsatellite instability (MSI), HER2 and ATM molecular subgroups of gastric cancer (GC).
H. K. Angell   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy