Results 121 to 130 of about 3,088,234 (360)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

On the experience of the sublime in architectural atmospheres: a phenomenological inquiry

open access: yesFrontiers in Psychology
The concept of the sublime has inspired numerous philosophical inquiries throughout the evolution of aesthetic thought. This article examines the type of experience referenced by philosophers in their discussions surrounding the concept of the sublime. I
Benedikte Kudahl
doaj   +1 more source

Thermal Processes Governing Hot-Jupiter Radii

open access: yes, 2013
There have been many proposed explanations for the larger-than-expected radii of some transiting hot Jupiters, including either stellar or orbital energy deposition deep in the atmosphere or deep in the interior.
Burrows, Adam, Spiegel, David S.
core   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Drivers of the rare persistence of sea ice in the western Chukchi Sea in summer 2024

open access: yesEnvironmental Research Letters
During the 2024 Arctic summer, an unexpected sea ice patch (∼100 000 km ^2 ) survived in the western Chukchi Sea, an event that has not occurred in the past 20 years.
Jiaxing Gong   +7 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Nichts anderes als Karfunkel

open access: yesInternationale Zeitschrift für Kulturkomparatistik
Nothing other than a carbuncle The carbuncle as a Christological symbol of atmosphere in Nicholas of Cusa - with reference to the late antique and medieval gemstone allegory.
Pilar Bücker
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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