Results 111 to 120 of about 1,221,396 (292)

The impact of environmental characteristics of place as sense of place elements on atmosphere perception: focusing on P/N evaluations of atmosphere experienced by Japan undergraduate in leisure places

open access: yesJournal of Asian Architecture and Building Engineering
The study of the relationship between the atmosphere of a place and the emotional response of users has been a key focus of traditional sense of place research.
Changguk Kim, Dongyun Kwak
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

On the experience of the sublime in architectural atmospheres: a phenomenological inquiry

open access: yesFrontiers in Psychology
The concept of the sublime has inspired numerous philosophical inquiries throughout the evolution of aesthetic thought. This article examines the type of experience referenced by philosophers in their discussions surrounding the concept of the sublime. I
Benedikte Kudahl
doaj   +1 more source

Atmosphere: He Luting ; Yang Yinliu. 10 1

open access: yes, 2015
Side A. 賀綠汀 -- Side B. 賀綠汀/楊蔭瀏.Live recording."Atmosphere 1979"--Side A label.Conversation on the train from Guangzhou to Changsha.Electronic reproduction from Rulan Chao Pian Audio Cassette Collection.Spoken in Chinese.Detailed contents in vernacular ...

core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Drivers of the rare persistence of sea ice in the western Chukchi Sea in summer 2024

open access: yesEnvironmental Research Letters
During the 2024 Arctic summer, an unexpected sea ice patch (∼100 000 km ^2 ) survived in the western Chukchi Sea, an event that has not occurred in the past 20 years.
Jiaxing Gong   +7 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

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