Results 91 to 100 of about 3,088,234 (360)

Methods to Investigate the Global Atmospheric Microbiome

Frontiers in Microbiology, 2019
The interplay between microbes and atmospheric physical and chemical conditions is an open field of research that can only be fully addressed using multidisciplinary approaches.
Aurelien Dommergue, Pierre Amato, Romie Tignat-Perrier, Romie Tignat-Perrier, Olivier Magand, Alban Thollot, Alban Thollot, Muriel Joly, Laetitia Bouvier, Karine Sellegri, Timothy Vogel, Jeroen E. Sonke, Jean-Luc Jaffrezo, Marcos Andrade, Marcos Andrade, Isabel Moreno, Casper Labuschagne, Lynwill Martin, Qianggong Zhang, Catherine Larose   +19 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Planetary atmosphere albedo [PDF]

Computation of plane and spherical albedo of planetary ...
Sobolev, V. V.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The self-screening Hawking atmosphere

, 1997
A model is proposed in which the Hawking particles emitted by a black hole are treated as an envelope of matter that obeys an equation of state, and acts as a source in Einstein's equations. This is a crude but interesting way to accommodate for the back
't Hooft, Bondi, Dai, Davies, Gerard 't Hooft, Hartle, Hawking, Israel, Landau, Maldacena, Oppenheimer, Polchinski, Sorkin, Thorne, Tolman, Unruh, Unruh, Zurek   +17 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

On the Decadal Modes of Oscillation of an Idealized Ocean-atmosphere System [PDF]

, 1990
Axially-symmetric, linear, free modes of global, primitive equation, ocean-atmosphere models are examined to see if they contain decadal (10 to 30 years) oscillation time scale modes.
Mehta, Vikram M.
core   +1 more source

Models of magnetized neutron star atmospheres: thin atmospheres and partially ionized hydrogen atmospheres with vacuum polarization

, 2009
Observed X-ray spectra of some isolated magnetized neutron stars display absorption features, sometimes interpreted as ion cyclotron lines. Modeling the observed spectra is necessary to check this hypothesis and to evaluate neutron star parameters.We ...
A. Y. Potekhin, Baiotti, Brown, Burwitz, Burwitz, Gänsicke, Haberl, Haberl, Ho, Ho, Ho, Ho, Ho, Ho, Ibragimov, K. Werner, Kaminker, Kaminker, Kaplan, Kaplan, Kaplan, Kaspi, Lai, Lai, Lattimer, Medin, Mereghetti, Mereghetti, Mereghetti, Mignani, Mori, Motch, Olson, Pavlov, Pavlov, Pavlov, Pons, Potekhin, Potekhin, Potekhin, Pérez-Azorín, Rajagopal, Rajagopal, Rauch, Romani, Sanwal, Schwope, Schwope, Shibanov, Suleimanov, Suleimanov, Swartz, Tiengo, Trümper, Turolla, V. Suleimanov, van Adelsberg, van Adelsberg, van Kerkwijk, Ventura, Zane, Zavlin, Zavlin, Özel   +63 more
core   +1 more source

Atmospheric Photochemistry [PDF]

, 2017
International ...
Lefèvre, Franck, Krasnopolsky, Vladimir
openaire   +3 more sources

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source