Results 71 to 80 of about 1,221,396 (292)

Thunderstorm Ground Enhancements Measured on Aragats and Progress of High-Energy Physics in the Atmosphere

open access: yes, 2023
High-energy physics in the atmosphere (HEPA) has undergone an intense reformation in the last decade. Correlated measurements of particle fluxes modulated by strong atmospheric electric fields, simultaneous measurements of the disturbances of the near ...
Ashot Chilingarian
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Diagnosis of Local Land-Atmosphere Feedbacks in India [PDF]

open access: yes, 2011
Following the convective triggering potential (CTP)–humidity index (HIlow) framework by Findell and Eltahir, the sensitivity of atmospheric convection to soil moisture conditions is studied for India.
Hutjes, R.W.A.   +7 more
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Atmospheric and Fog Effects on Ultra-Wide Band Radar Operating at Extremely High Frequencies

open access: yesSensors, 2016
The wide band at extremely high frequencies (EHF) above 30 GHz is applicable for high resolution directive radars, resolving the lack of free frequency bands within the lower part of the electromagnetic spectrum.
Nezah Balal   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Ein internes Vorhersagbarkeitsexperiment im Lorenz Modell

open access: yesMeteorologische Zeitschrift, 1995
Die Vorhersagbarkeit der Atmosphäre wird vielfach durch die klassischen Größen der Fehlerverdopplungszeit und des Vorhersagbarkeitsendes quantifiziert. Diese Maße sind mittlere Zeiten, nach denen kleine Anfangsfehler sich verdoppelt bzw. einen bestimmten
Christine Ziehmann-Schlumbohm   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy