Results 71 to 80 of about 1,221,396 (292)
High-energy physics in the atmosphere (HEPA) has undergone an intense reformation in the last decade. Correlated measurements of particle fluxes modulated by strong atmospheric electric fields, simultaneous measurements of the disturbances of the near ...
Ashot Chilingarian
core +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Diagnosis of Local Land-Atmosphere Feedbacks in India [PDF]
Following the convective triggering potential (CTP)–humidity index (HIlow) framework by Findell and Eltahir, the sensitivity of atmospheric convection to soil moisture conditions is studied for India.
Hutjes, R.W.A. +7 more
core +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Atmospheric and Fog Effects on Ultra-Wide Band Radar Operating at Extremely High Frequencies
The wide band at extremely high frequencies (EHF) above 30 GHz is applicable for high resolution directive radars, resolving the lack of free frequency bands within the lower part of the electromagnetic spectrum.
Nezah Balal +2 more
doaj +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Ein internes Vorhersagbarkeitsexperiment im Lorenz Modell
Die Vorhersagbarkeit der Atmosphäre wird vielfach durch die klassischen Größen der Fehlerverdopplungszeit und des Vorhersagbarkeitsendes quantifiziert. Diese Maße sind mittlere Zeiten, nach denen kleine Anfangsfehler sich verdoppelt bzw. einen bestimmten
Christine Ziehmann-Schlumbohm +2 more
doaj +1 more source

