Results 61 to 70 of about 3,088,234 (360)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

High Resolution, Differential, Near-infrared Transmission Spectroscopy of GJ 1214b

, 2011
The nearby star GJ 1214 hosts a planet intermediate in radius and mass between Earth and Neptune, resulting in some uncertainty as to its nature. We have observed this planet, GJ 1214b, during transit with the high-resolution, near-infrared NIRSPEC ...
Andrae, Barman, Barman, Berta, Borucki, Brad M. S. Hansen, Carter, Claret, Croll, Croll, Deming, Donati, Désert, Hinkle, I. J. M. Crossfield, Irwin, Joliffe, Lord, Madhusudhan, Mandel, Mandell, Miller-Ricci, Miller-Ricci, Nettelmann, Redfield, Rogers, Rogers, Rojas-Ayala, Sing, Travis Barman, Zahnle   +30 more
core   +1 more source

Atmospheric Neutrinos [PDF]

AIP Conference Proceedings, 2007
6 pages, 5 figures. This paper is an expanded version of a paper of the same name to appear the Proceedings of TAUP 2015 in the Journal of Physics Conference ...
Thomas K. Gaisser, Jeffrey R. Wilkes
openaire   +4 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Atmospheric and Fog Effects on Ultra-Wide Band Radar Operating at Extremely High Frequencies

Sensors, 2016
The wide band at extremely high frequencies (EHF) above 30 GHz is applicable for high resolution directive radars, resolving the lack of free frequency bands within the lower part of the electromagnetic spectrum.
Nezah Balal, Gad A. Pinhasi, Yosef Pinhasi   +2 more
doaj   +1 more source

Microwave spectroscopy of the Mars atmosphere [PDF]

, 1995
A study of the use of millimeter-wavelength spectral transitions to investigate the atmosphere of Mars is presented. In the model experiments investigated it is assumed that a spectrometer in the frequency range from 100 to 260 GHz looks into a modest ...
Clancy, R. T., Muhleman, D. O.
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Ein internes Vorhersagbarkeitsexperiment im Lorenz Modell

Meteorologische Zeitschrift, 1995
Die Vorhersagbarkeit der Atmosphäre wird vielfach durch die klassischen Größen der Fehlerverdopplungszeit und des Vorhersagbarkeitsendes quantifiziert. Diese Maße sind mittlere Zeiten, nach denen kleine Anfangsfehler sich verdoppelt bzw. einen bestimmten
Christine Ziehmann-Schlumbohm, Klaus Fraedrich, Leonard A. Smith   +2 more
doaj   +1 more source

Cuerpo, Atmósfera y Tipología Climática: hacia una Arquitectura de la Vida Cotidiana = Body, Atmosphere, and Climatic Typology: toward an Architecture for Everyday Life

Cuadernos de Proyectos Arquitectónicos, 2020
Resumen A lo largo de las últimas dos décadas, y ante la creciente preocupación por el medio ambiente y el cambio climático, la arquitectura ha explorado las oportunidades abiertas por los campos de la termodinámica y la ecología.
Javier García-Germán
doaj   +1 more source