Results 141 to 150 of about 3,054,495 (336)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Strong Localized Pumping of Water Vapor to High Altitudes on Mars During the Perihelion Season

Geophysical Research Letters
Here we present water vapor vertical profiles observed with the ExoMars Trace Gas Orbiter/Nadir and Occultation for MArs Discovery instrument during the perihelion and Southern summer solstice season (LS = 240°–300°) in three consecutive Martian Years 34,
A. Brines, M. A. López‐Valverde, B. Funke, F. González‐Galindo, S. Aoki, G. L. Villanueva, J. A. Holmes, D. A. Belyaev, G. Liuzzi, I. R. Thomas, J. T. Erwin, U. Grabowski, F. Forget, J. J. Lopez‐Moreno, J. Rodriguez‐Gomez, F. Daerden, L. Trompet, B. Ristic, M. R. Patel, G. Bellucci, A. C. Vandaele   +20 more
doaj   +1 more source

Unsettling the settled: simple musings on the complex climatic system

Frontiers in Complex Systems
Our revisit of fundamental issues of climate challenges the notion and term of the “greenhouse effect”, and attempts a scientific reevaluation using minimal assumptions, such as Newton’s laws, maximum entropy and gas spectroscopy. It replaces terms like “
Demetris Koutsoyiannis, George Tsakalias
doaj   +1 more source

Evolution of the atmosphere [PDF]

Theories on the origin of the Earth atmosphere and chemical composition are presented. The role of oxygenic photosynthesis on the determination of the Earth's origin is discussed.
Kasting, J. F.
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

On the Budget and Atmospheric Fate of Sulfur Emissions From Large Volcanic Eruptions

Geophysical Research Letters
Today, volcanic sulfur emissions into the atmosphere are measured spectroscopically from the ground, air and space. For eruptions prior to the satellite era, two main sulfur proxies are used, the rock and ice core records, as illustrated by Peccia et al.
Bruno Scaillet, Clive Oppenheimer
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

The impact of environmental characteristics of place as sense of place elements on atmosphere perception: focusing on P/N evaluations of atmosphere experienced by Japan undergraduate in leisure places

Journal of Asian Architecture and Building Engineering
The study of the relationship between the atmosphere of a place and the emotional response of users has been a key focus of traditional sense of place research.
Changguk Kim, Dongyun Kwak
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

CLASSROOM ATMOSPHERE

, 2022
The paper presents the results of the research which aimed at determining primary school teachers’ (N=555) attitudes to maintaining discipline and classroom atmosphere during the teaching process, as well as to investigate the correlation of attitudes from two sociodemographic characteristics: sex and teaching experience.
Kadum, Sandra, Lazarić, Lorena, Drandić, Dijana   +2 more
openaire   +2 more sources