Results 51 to 60 of about 113,594 (358)

The present and past climates of planet Mars

EPJ Web of Conferences, 2009
Mars is a small planet with a thin atmosphere of almost pure carbon dioxide. To first order, the Martian meteorology can be compared with what one would expect on a cold, dry desert-like Earth.
Forget F.
doaj   +1 more source

Trace gas assimilation of Mars orbiter observations [PDF]

, 2012
Ozone, water vapour and argon are minor constituents in the Martian atmosphere, observations of which can be of use in constraining atmospheric dynamical and physical processes.
Holmes, J. A., Lewis, S. R., Patel, M. R.   +2 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

MISSION PROFILE AND DESIGN CHALLENGES FOR MARS LANDING EXPLORATION [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2017
An orbiter and a descent module will be delivered to Mars in the Chinese first Mars exploration mission. The descent module is composed of a landing platform and a rover.
J. Dong, Z. Sun, W. Rao, Y. Jia, L. Meng, C. Wang, B. Chen   +6 more
doaj   +1 more source

Breeding vectors and predictability in the Oxford Mars GCM [PDF]

, 2003
A breeding vectors approach is used to study the intrinsic predictability of the Martian atmosphere using the Oxford Mars General Circulation Model (MGCM).
Lewis, S.R., Newman, C.E., Read, P.L.
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Turbulence in the Lower Atmosphere of Mars Enhanced by Transported Dust Particles [PDF]

, 2021
Aymeric Spiga
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Effects of the 2018 Martian Global Dust Storm on Boundary Positions in the Induced Magnetosphere

The Planetary Science Journal
Global dust storms at Mars have a significant impact on the atmosphere and ionosphere, but only recently has their impact on the magnetosphere been investigated.
Catherine E. Regan, Andrew J. Coates, Mark Lester, Anne Wellbrock, Geraint H. Jones, Beatriz Sánchez-Cano, Philippe Garnier, Louisa J. Preston, František Němec, Václav Linzmayer, Rudy A. Frahm, Mats Holmström   +11 more
doaj   +1 more source