Results 51 to 60 of about 399,430 (333)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Gas Giant Simulations of Eddy‐Driven Jets Accompanied by Deep Meridional Circulation
Jupiter's atmosphere comprises several dynamical regimes: the equatorial eastward flows and surrounding retrograde jets; the midlatitudes, with the eddy‐driven, alternating jet‐streams and meridional circulation cells; and the jet‐free turbulent polar ...
Keren Duer, Eli Galanti, Yohai Kaspi
doaj +1 more source
Only a low percentage of the radiation from our Sun is captured by photosynthesis, but this conversion of solar to chemical energy sustains all life on Earth.
Pablo Marcos-Arenal +7 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
A GCM study of the response of the atmospheric water cycle of West Africa and the Atlantic to Saharan dust radiative forcing [PDF]
The responses of the atmospheric water cycle and climate of West Africa and the Atlantic to radiative forcing of Saharan dust are studied using the NASA finite volume general circulation model (fvGCM), coupled to a mixed layer ocean.
K. M. Lau +3 more
doaj +1 more source
Doppler-Shifted Alkali D Absorption as Indirect Evidence for Exomoons
Sodium and potassium signatures in transiting exoplanets can be challenging to isolate from the stellar absorption lines. Here, these challenges are discussed in the framework of Solar System observations, and transits of Mercury in particular. Radiation
Carl A. Schmidt
doaj +1 more source
We aim to show the importance of non-elastic excitation and deexcitation processes in $\textrm{He}^{*}(n)+ \textrm{He}(1s^{2})$ collisions with the principal quantum number $n \ge 3$ for helium-rich white dwarf atmospheres. We compare the efficiencies of
Dimitrijevic, M. S. +3 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
We present new results of our studies of zonal and meridional winds in both hemispheres of Venus, using ground- and space-based coordinated observations.
Pedro Machado +8 more
doaj +1 more source
Observations of Exoplanet Atmospheres
Detailed characterization of an extrasolar planet's atmosphere provides the best hope for distinguishing the makeup of its outer layers, and the only hope for understanding the interplay between initial composition, chemistry, dynamics & circulation, and
Crossfield, Ian J. M.
core +1 more source

