Results 61 to 70 of about 391,633 (331)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

The atmospheric circulation of the super Earth GJ 1214b: Dependence on composition and metallicity [PDF]

open access: yes, 2014
We present three-dimensional atmospheric circulation models of GJ 1214b, a 2.7 Earth-radius, 6.5 Earth-mass super Earth detected by the MEarth survey.
Fortney, Jonathan J.   +4 more
core   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Re-reading Whitehead Through the Pre‑reflective Experience of Atmospheric Processes

open access: yesAmbiances, 2021
This article explores new perspectives on Alfred N. Whitehead’s process philosophy through a micro-phenomenological investigation of the experience of atmospheres.
Desiree Foerster
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Space cabin atmospheres [PDF]

open access: yes, 1964
Space cabin atmospheres - physical and physiological ...
Roth, E. M.
core   +1 more source

The Atmospheric Signatures of Super-Earths: How to Distinguish Between Hydrogen-Rich and Hydrogen-Poor Atmospheres

open access: yes, 2008
Extrasolar super-Earths (1-10 M$_{\earth}$) are likely to exist with a wide range of atmospheres. Some super-Earths may be able to retain massive hydrogen-rich atmospheres.
Adams   +41 more
core   +1 more source

The recondite intricacies of Zeeman Doppler mapping [PDF]

open access: yes, 2011
We present a detailed analysis of the reliability of abundance and magnetic maps of Ap stars obtained by Zeeman Doppler mapping (ZDM). It is shown how they can be adversely affected by the assumption of a mean stellar atmosphere instead of appropriate ...
Alecian   +50 more
core   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

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