Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger +5 more
wiley +1 more source
Single‐crystalline LaOCl and GdOCl form atomically abrupt, Cl‐terminated interfaces with MoS2, enabling near‐ideal switching and suppressed flicker noise. Carrier‐number‐fluctuation analysis yields effective noise‐derived interface trap densities of 1.15–1.94 × 1010 cm−2 eV−1, approaching hexagonal boron nitride levels with high‐κ coupling.
Chanho Lee +10 more
wiley +1 more source
Spatially distributing Ti3C2Tx nanosheets into core‐shell architecture, rather than as directly dispersed flakes, mitigates aggregation and enhances photon harvesting. When the Ti3C2Tx core‐shell particles are incorporated into a shape‐memory polymer matrix at an ultralow loading of 0.0024 wt%, the improved photothermal conversion translates into ...
May Maung Zaw +12 more
wiley +1 more source
Atmospheric and Geogenic Controls of Rainwater and Stream-Water Chemistry in an Aleppo-Pine-Dominated Mediterranean Karst Catchment. [PDF]
Butorac L +5 more
europepmc +1 more source
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar +11 more
wiley +1 more source
How the Porous Transport Layer Dictates Membrane Electrode Assembly Performance of IrO2 Catalysts
The Schottky barrier formed at the catalyst | PTL interface critically governs both the initial performance and long‐term durability of the PEMWE, and its magnitude is dictated by the catalyst's work function. This limitation can be resolved by combining a rutile IrO2 core for efficient electron transfer with an amorphous IrOx shell for high surface ...
Hyeseong Jeon +6 more
wiley +1 more source
Heteroengineering‐Induced Electronic Reconstruction for Ammonium‐Ion Energy Storage
An integrated electronic reconstruction behavior is induced by local heteroengineering on VO2(B) electrode material surface of NH4+ supercapacitor, rationally modulating the electronic structure, enabling enhanced intrinsic conductivity and extra driving force for NH4+ intercalation reaction.
Ji‐Chi Liu +11 more
wiley +1 more source
The Emergence of an Urable Earth: How Early Planetary Evolution Shaped the Chemical Window for Life's Origin. [PDF]
Guo M, Meng Z, Liu S, Redfern SAT.
europepmc +1 more source
Rethinking hydrothermal vents: a structural ecology perspective on the early emergence of metabolic roles. [PDF]
Kato S.
europepmc +1 more source
Computational Study of Gas-Phase Reactions to Produce Sulfite Esters: A New Class of Sulfur Containing Molecules in the Atmosphere? [PDF]
Daub CD, Kumar A, Rissanen M.
europepmc +1 more source

