Results 81 to 90 of about 3,768,335 (339)

Instrumentation on commercial aircraft for monitoring the atmospheric composition on a global scale: the IAGOS system, technical overview of ozone and carbon monoxide measurements

, 2015
This article presents the In-service Aircraft of a Global Observing System (IAGOS) developed for operations on commercial long-range Airbus aircraft (A330/A340) for monitoring the atmospheric composition.
P. Nédélec, R. Blot, D. Boulanger, G. Athier, J. Cousin, Benoit Gautron, A. Petzold, A. Volz-Thomas, V. Thouret   +8 more
semanticscholar   +1 more source

Limitation of Atmospheric Composition by Combustion–Explosion in Exoplanetary Atmospheres [PDF]

The Astrophysical Journal, 2018
Abstract This work presents theoretical studies that combine aspects of combustion and explosion theory with exoplanetary atmospheric science. Super-Earths could possess a large amount of molecular hydrogen depending on disk, planetary, and stellar properties.
John Lee Grenfell, Barbara Stracke, Mareike Godolt, Stefanie Gebauer, Heike Rauer, Heike Rauer, Ralph Lehmann   +6 more
openaire   +5 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Soot Particle Agglomeration Inlet (SPAI) for Enabling Online Chemical Composition Measurement of Nanoparticles with the Aerosol Mass Spectrometer

Aerosol and Air Quality Research, 2021
Nanoparticles are a topic of interest because of their effects on human health and the climate, but the current options for evaluating their chemical composition—one of the key properties that determine the mechanisms of these effects—remain very limited
Sampsa Martikainen, Sanna Saarikoski, Paxton Juuti, Hilkka Timonen, Jorma Keskinen, Panu Karjalainen   +5 more
doaj   +1 more source

Atmospheric CO2 effect on stable carbon isotope composition of terrestrial fossil archives

Nature Communications, 2018
The 13C/12C ratio of C3 plant matter is thought to be controlled by the isotopic composition of atmospheric CO2 and stomatal response to environmental conditions, particularly mean annual precipitation (MAP).
Vincent J. Hare, E. Loftus, A. Jeffrey, C. Ramsey   +3 more
semanticscholar   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Measurement report: Wintertime aerosol characterization at an urban traffic site in Helsinki, Finland [PDF]

Atmospheric Chemistry and Physics
Physical and chemical properties of particulate matter and concentrations of trace gases were measured at an urban site in Helsinki, Finland, for 5 weeks to investigate the effect of wintertime conditions on pollutants.
K. Teinilä, S. Saarikoski, H. Lintusaari, T. Lepistö, P. Marjanen, M. Aurela, H. Hellén, T. Tykkä, M. Lampimäki, J. Lampilahti, L. Barreira, T. Mäkelä, L. Kangas, J. Hatakka, S. Harni, J. Kuula, J. V. Niemi, H. Portin, J. Yli-Ojanperä, J. Yli-Ojanperä, V. Niemelä, M. Jäppi, K. Lehtipalo, K. Lehtipalo, J. Vanhanen, L. Pirjola, L. Pirjola, H. E. Manninen, T. Petäjä, T. Rönkkö, H. Timonen   +30 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Evaluation of the performance of a particle concentrator for online instrumentation [PDF]

Atmospheric Measurement Techniques, 2014
The performance of the miniature Versatile Aerosol Concentration Enrichment System (m-VACES; Geller et al., 2005) was investigated in laboratory and field studies using online instruments. Laboratory tests focused on the behavior of monodisperse ammonium
S. Saarikoski, S. Carbone, M. J. Cubison, R. Hillamo, P. Keronen, C. Sioutas, D. R. Worsnop, J. L. Jimenez   +7 more
doaj   +1 more source