Results 61 to 70 of about 597,424 (306)

Composition of Titan's Atmosphere [PDF]

open access: yes, 2021
As a result of the 13-year exploration of the Saturn system by the Cassini-Huygens mission (2004–17), there has been a revolution in our understanding of Titan, Saturn's largest satellite. Titan's atmosphere shows the most complex chemistry in the solar system.
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The applicability and challenges of black carbon sensors in monitoring networks [PDF]

open access: yesAerosol Research
Black carbon (BC) is a particulate pollutant emitted as a by-product of combustion. BC has an emerging role in air quality monitoring with the current recommendations by the World Health Organization to monitor BC to capture its temporal and spatial ...
J. T. Elomaa   +6 more
doaj   +1 more source

Snow Samples Combined With Long-Range Transport Modeling to Reveal the Origin and Temporal Variability of Black Carbon in Seasonal Snow in Sodankylä (67°N)

open access: yesFrontiers in Earth Science, 2020
In the Arctic areas, the influence of global climate change is enhanced. Enabling a better understanding of the changes in the Arctic environment is of the utmost importance.
Outi Meinander   +4 more
doaj   +1 more source

The Atmospheric Chemistry and Climate Model Intercomparison Project (ACCMIP): Overview and description of models, simulations and climate diagnostics [PDF]

open access: yes, 2013
The Atmospheric Chemistry and Climate Model Intercomparison Project (ACCMIP) consists of a series of time slice experiments targeting the long-term changes in atmospheric composition between 1850 and 2100, with the goal of documenting composition changes
Bergmann, D.   +29 more
core   +4 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Atmospheric Retrieval for Super-Earths: Uniquely Constraining the Atmospheric Composition with Transmission Spectroscopy

open access: yes, 2011
We present a retrieval method based on Bayesian analysis to infer the atmospheric compositions and surface or cloud-top pressures from transmission spectra of exoplanets with general compositions.
Benneke, Bjoern, Seager, Sara
core   +1 more source

The atmospheric circulation of the super Earth GJ 1214b: Dependence on composition and metallicity [PDF]

open access: yes, 2014
We present three-dimensional atmospheric circulation models of GJ 1214b, a 2.7 Earth-radius, 6.5 Earth-mass super Earth detected by the MEarth survey.
Fortney, Jonathan J.   +4 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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