Results 131 to 140 of about 744,956 (222)

Clinical Significance of a Cell‐Of‐Origin‐Based Classification in Pancreatic Ductal Adenocarcinoma

Cancer Science, EarlyView.
Schematic overview of a cell‐of‐origin‐based classification of pancreatic ductal adenocarcinoma (PDAC), highlighting distinct biological features and therapeutic implications of Acinar‐ and Ductal‐subtypes. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with limited therapeutic options and poor clinical ...
Tatsuya Kikuchi, Soichiro Ako, Hironari Kato, Hideaki Kinugasa, Masaki Uchida, Takashi Oda, Ryosuke Hirai, Akihiro Matsumi, Kazuya Miyamoto, Hiroyuki Terasawa, Yuki Fujii, Daisuke Uchida, Kazuyuki Matsumoto, Koichiro Tsutsumi, Shigeru Horiguchi, Kazuya Yasui, Tomokazu Fuji, Kosei Takagi, Hirokazu Kato, Tomoyuki Honda, Fumio Otsuka, Motoyuki Otsuka   +21 more
wiley   +1 more source

Reducing whale–vessel strikes through multiobjective vessel traffic routing

Conservation Biology, EarlyView.
Abstract Vessel strikes threaten many large whale species. Managers employ several mitigation measures to reduce vessel strike risk, including establishing or modifying vessel routing measures, such as shipping lanes. However, most studies utilized to inform the configuration of shipping lanes only consider a limited number of potential lanes, and in ...
Lisa Neyman, Nathan Crum
wiley   +1 more source

Evaluating the Scale of Natural and Mechanical Airflows for Surface-Based Atmospheric Pollutant Removal. [PDF]

Environ Sci Technol
Tomlinson SD, Tsopelakou AM, Onn TM, Barrett SRH, Boies AM, Fitzgerald SD.   +5 more
europepmc   +1 more source

Mesenchymal stromal cell‐derived extracellular vesicles improve islet β‐cell metabolic function via miRNA‐mediated regulation of Ankyrin‐B expression

Diabetic Medicine, EarlyView.
Abstract Aims Mesenchymal stromal‐cell‐derived extracellular vesicles (MSC‐EVs) improve islet function, which may be mediated in part through the delivery of microRNAs (miRNAs) to β‐cells. To investigate the underlying mechanisms, we identified the most abundant MSC‐EV miRNAs, their relative transfer to β‐cells and the extent to which Ankyrin‐B (Ank2 ...
Tzu‐Wen Hong, Ryea Arora, Rosie Sullivan, Zekun Lyu, William T. Blackstone Whines, Lydia F. Daniels Gatward, Ella L. Hubber, Tien‐Chi Huang, Aileen J. F. King, Shanta J. Persaud, Peter M. Jones   +10 more
wiley   +1 more source

A dataset on morphology and composition of saltation-sandblasting dust particles from major Chinese source regions. [PDF]

Sci Data
Zhang L, Hu T, Song Y, Yuan Y, Wu F, Huang Y, Zhang D, Cao J.   +7 more
europepmc   +1 more source

The aesthetic sublime of megaproject structures: A framework and a research agenda

European Management Review, EarlyView.
Abstract The physical structures of megaprojects—such as mega‐canals, metros, railway lines, bridges, tunnels, and iconic opera houses—hold a profound capacity to generate aesthetic experiences with enduring societal impact. Yet, research on megaprojects has predominantly focused on functionality and economic rationale with aesthetics being pushed to ...
Federica De Molli, Alfons van Marrewijk, Arne Carlsen   +2 more
wiley   +1 more source

Broadband 2-µm fiber-laser supercontinuum for high-resolution optical coherence tomography. [PDF]

Biomed Opt Express
Zhang R, Kitajima S, Kokinda J, Nishizawa N.   +3 more
europepmc   +1 more source

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

The FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo, Evodie Peperstraete, Léa Mabille, Joséphine Louvieaux, Jim Marmuse, Clément Lecerf, Chann Lagadec, Xuefen Le Bourhis, Éric Adriaenssens   +8 more
wiley   +1 more source

Unexpectedly rapid SO₂ heterogeneous reaction on the surface of vehicular brake wear particles. [PDF]

Nat Commun
Qi F, Liang X, Zeng Y, Qi C, Liang Z, Liu X, Men Z, Fang T, Guo J, Ma Y, Wang H, Zhang X, Zhang J, Wang W, Jiang S, Wu L, Zhang T, Ge M, Shao M, Mao H, Peng J.   +20 more
europepmc   +1 more source

Hydropower Regulation of Xingu River Discharge Structures Heterogeneous, Sector‐Specific Responses in Pacu Fisheries Along the River Continuum

Fisheries Management and Ecology, EarlyView.
ABSTRACT Hydroelectric dams are common in Amazonian tributaries under federal environmental licensing that requires long‐term fisheries monitoring. This study evaluated three fishing systems targeting “pacu” species (Serrasalmidae) in the Xingu River before, during, and after construction of the Belo Monte dam (2012–2023) across four river sectors ...
João Paulo Moura de Queiroz, Nelson de Almeida Gouveia, Marcelo Ândrade, Rafael Paiva de Oliveira Diaz, Claudemir Oliveira da Silva, Victoria J. Isaac   +5 more
wiley   +1 more source