Results 71 to 80 of about 1,003,860 (311)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Satellite-based links for quantum key distribution: beam effects and weather dependence
New Journal of Physics, 2019 The establishment of a world-wide quantum communication network relies on the synergistic integration of satellite-based links and fiber-based networks. The first are helpful for long-distance communication, as the photon losses introduced by the optical
Carlo Liorni +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
International Journal of Digital EarthTraditional Interferometric Synthetic Aperture Radar (InSAR) methods have difficulties in capturing deformation information of small and medium-sized earthquakes due to small surface deformation and atmospheric interference.
Xuedong Zhang +4 more
doaj +1 more source
Theoretical study of lepton events in the atmospheric neutrino experiments at SuperK
, 2009 Super-Kamiokande has reported the results for the lepton events in the atmospheric neutrino experiment. These results have been presented for a 22.5kT water fiducial mass on an exposure of 1489 days, and the events are divided into sub-GeV, multi-GeV and
A. Bandyopadhyay +114 more
core +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Combining LSND and Atmospheric Anomalies in a Three-Neutrino Picture [PDF]
, 2001 We investigate the three-neutrino mixing scheme for solving the atmospheric and LSND anomalies. We find the region in the parameter space that provides a good fit to the LSND and the SK atmospheric data, taking into account the CHOOZ constraint.
Barenboim, G., Dighe, A., Skadhauge, S.
core +2 more sources
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Atmospheric effects on oblique impacts [PDF]
Laboratory experiments and theoretical calculations often use vertical impact angles (90 deg) in order to avoid the complicating effect of asymmetry.
Schultz, P. H.
core +1 more source