Results 61 to 70 of about 6,623 (297)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Experimental Evaluation of the Blackbody Radiation Shift in the Cesium Atomic Fountain Clock

open access: yesApplied Sciences, 2022
The cesium atomic fountain clock is the world’s most accurate microwave atomic clock. The uncertainty of blackbody radiation (BBR) shift accounts for an increasingly large percentage of the uncertainty associated with fountain clocks and has become a key
Fan Yang   +10 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A chip scale atomic clock driven receiver for multi-constellation GNSS [PDF]

open access: yes, 2013
This paper presents the design and implementation of a Chip Scale Atomic Clock (CSAC) driven dual-channel Digitally Configurable Receiver (DCR) for Global Navigation Satellite Systems (GNSS).
Berry, R.   +5 more
core   +1 more source

Physicist David Glaze with atomic clock NBS-6 [PDF]

open access: yes
This image is part of the Atomic Clock collection. The Atomic Clock collection is comprised of images documenting the development of the atomic clocks that were part of the National Bureau of Standards (NBS) Atomic Time System.
National Institute of Standards and Technology and Technology
core   +6 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Simulation of the Effect of Improved Ground Clocks on GPS Timing Performance [PDF]

open access: yes, 2010
The GPS system is simulated in three scenarios, so as to estimate how its performance would be improved by more stable ground clocks. One scenario is an approximation to the current system.
Demetrios Matsakis   +3 more
core   +1 more source

Atomic clock NBS-6 [PDF]

open access: yes
This image is part of the Atomic Clock collection. The Atomic Clock collection is comprised of images documenting the development of the atomic clocks that were part of the National Bureau of Standards (NBS) Atomic Time System.
National Institute of Standards and Technology and Technology
core   +2 more sources

NBS atomic clock equipment [PDF]

open access: yes
This image is part of the Atomic Clock collection. The Atomic Clock collection is comprised of images documenting the development of the atomic clocks that were part of the National Bureau of Standards (NBS) Atomic Time System.
National Institute of Standards and Technology and Technology
core   +2 more sources

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