Results 71 to 80 of about 6,623 (297)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Cold atom microwave clock based on intracavity cooling in China space station
Atomic clocks with higher frequency stability and accuracy than traditional space-borne atomic clocks are the cornerstone of long-term autonomous operation of space-time-frequency systems.
Siminda Deng +11 more
doaj +1 more source
Optical atomic clock comparison through turbulent air
We use frequency-comb-based optical two-way time-frequency transfer (O-TWTFT) to measure the optical frequency ratio of state-of-the-art ytterbium and strontium optical atomic clocks separated by a 1.5-km open-air link.
Martha I. Bodine +34 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Improving the Q Factor of an Optical Atomic Clock Using Quantum Nondemolition Measurement
Quantum nondemolition (QND) measurement is a remarkable tool for the manipulation of quantum systems. It allows specific information to be extracted while still preserving fragile quantum observables of the system.
William Bowden +4 more
doaj +1 more source
Blackbody radiation shift in strontium lattice clocks revisited
We reevaluate the blackbody radiation (BBR) induced ac-Stark shift of the strontium clock transition (5s5p)^{3}P_{0}-(5s^{2})^{1}S_{0} at 698nm used as reference in optical lattice clocks and as secondary representation of the SI unit “second.” At room ...
Ch. Lisdat +3 more
doaj +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Allen Astin with atomic clock [PDF]
This image is part of the Atomic Clock collection. The Atomic Clock collection is comprised of images documenting the development of the atomic clocks that were part of the National Bureau of Standards (NBS) Atomic Time System.
National Institute of Standards and Technology and Technology
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