Results 61 to 70 of about 6,243,018 (311)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Physics Section Progress Report

open access: yes, 1955
Report discussing the progress of various projects at the Knolls Atomic Power Laboratory during the period from June to August ...
Knolls Atomic Power Laboratory
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Atomic Energy Commission Report AECD-3792

open access: yes, 1955
Report discussing the progress of various projects at the Knolls Atomic Power Laboratory during the period from March to May ...
Knolls Atomic Power Laboratory
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Nuclear Physics Section Progress Report

open access: yes, 1955
Report discussing the progress of various projects at the Knolls Atomic Power Laboratory during the period from September to November ...
Knolls Atomic Power Laboratory
core  

Calculation of the Mott Scattering cross section for Iron and Silver in the energy range (50keV-10MeV)

open access: yesTikrit Journal of Pure Science, 2018
In the present research work, we tableted  the ratio of Mott to Rutherford cross section ( ), for Iron and Silver atoms by employing Mckinley - Fashbach equation , in the range of incident electron energy (50KeV-10MeV), by adopting the equations used in
Muneer Ramadan Badah   +1 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Atomic Energy Commission Report TID-7546 Book 1

open access: yes, 1958
Preface: The Fuel Elements Conference held in Paris, France, November 18 to 23, 1957, under the joint sponsorship of the U.S. Atomic Energy Commission and the French Commissarat à l'Energie Atomique (CEA), provided an intensive review of fuel-element ...
U.S. Atomic Energy Commission
core  

A Simple Panel Unit Root Test in the Presence of Cross Section Dependence [PDF]

open access: yes, 2003
A number of panel unit root tests that allow for cross section dependence have been proposed in the literature, notably by Bai and Ng (2002), Moon and Perron (2003) and Phillips and Sul (2002) who use orthogonalization type procedures to asymptotically
M. Hashem Pesaran
core   +2 more sources

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