Results 61 to 70 of about 424,634 (266)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

ATOMIC and Molecular Data [PDF]

Symposium - International Astronomical Union, 1978
Excitation, ionization and recombination processes are discussed elsewhere in this volume by Seaton (1977). I will restrict my attention to those processes involving heavy particles that may modify the ionization structure of planetary nebulae and that may affect the molecular composition of condensations and of the transition regions between the ...
openaire   +1 more source

Critical Benchmark Validation of the Core Physics Multigroup Cross-Section Library TPEX

Energies
Core physics multigroup cross-section libraries provide essential cross-section and burnup data for reactor neutron physics calculations, serving as a fundamental prerequisite for reactor physics analysis.
Ying Chen, Haicheng Wu, Lili Wen, Yue Xiao, Jinchao Zhang, Qian Zhang, Xiaofei Wu, Huanyu Zhang   +7 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Accurate pulse time distribution determination using MLEM algorithm in integral experiments

Nuclear Engineering and Technology
Integral experiments play a crucial role in advancing nuclear science and technology by providing critical data that validate theoretical models and enhance reactor designs.
S.Y. Zhang, Y.B. Nie, Y.Y. Ding, Q. Zhao, K.Z. Xu, X.Y. Pan, H.T. Chen, Q. Sun, Z. Wei   +8 more
doaj   +1 more source

Notes on Critical Assessment of Theoretical Calculations of Atomic Structure and Transition Probabilities

Atoms, 2013
Atomic structure and transition probabilities are fundamental physical data required in many fields of science and technology. Atomic physics codes are freely available to other community users to generate atomic data for their interest, but the quality ...
Hyun-Kyung Chung, Per Jönsson, Alexander Kramida   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The cross sections and energy spectra of the particle emission in proton induced reaction on 204,206,207,208Pb and 209Bi

EPJ Web of Conferences, 2017
All cross sections of proton induced reactions, angular distributions, energy spectra and double differential cross sections of neutron, proton, deuteron, triton, helium and alpha-particle emissions for p+ 204,206,207,208Pb, 209Bi reactions are ...
Zhang Zhengjun, Liang Haiying, Xu Yongli, Han Yinlu, Cai Chonghai, Shen Qingbiao   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source