Results 331 to 340 of about 613,647 (384)

Atomic Force Microscopy (AFM)

Current Protocols in Microbiology, 2008
AbstractThe atomic force microscope (AFM) is an important tool for studying biological samples due to its ability to image surfaces under liquids. The AFM operates by physical interaction of a cantilever tip with the molecules on the cell surface. Adhesion forces between the tip and cell surface molecules are detected as cantilever deflections.
Andreea Trache, Gerald A. Meininger
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Atomic Force Microscopy

1993
Abstract This chapter discusses atomic force microscopy (AFM), focusing on the methods for atomic force detection. Although the force detection always requires a cantilever, there are two types of modes: the static mode and the dynamic mode. The general design and the typical method of manufacturing of the cantilevers are discussed.
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Atomic Force Microscopy of the Proteasome

2005
The proteasome should be an ideal molecule for studies on large enzymatic complexes, given its multisubunit and modular structure, compartmentalized design, numerous activities, and its own means of regulation. Considering the recent increased interest in the ubiquitin-proteasome pathway, it is surprising that biophysical approaches to study this ...
Maria Gaczynska, Pawel A. Osmulski
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Atomic Force Microscopy and Proteins

Protein & Peptide Letters, 2002
This review briefly introduces the principles of atomic force microscopy (AFM) applied to protein samples. AFM provides three-dimensional surface images of the proteins with high resolution. The advantage of AFM for protein studies is that AFM can visualize directly the molecule under physiological conditions without previous treatment. AFM operated in
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Force spectroscopy of single cells using atomic force microscopy

Nature Reviews Methods Primers, 2021
Albertus Viljoen, Marion Mathelié-Guinlet, Ankita Ray, Nico Strohmeyer, Y. J. Oh, P. Hinterdorfer, D. Müller, D. Alsteens, Y. Dufrêne   +8 more
semanticscholar   +1 more source

Can atomic force microscopy tips be inspected by atomic force microscopy?

Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures Processing, Measurement, and Phenomena, 1991
An attempt has been made to image prospective tips by atomic force microscopy. The apex of mounted diamond fragments and of traditional metallic tips was investigated by the same diamond probe. The peculiar tip–tip configuration allowed to search for the effect of sample rotation on the images.
Koen Waeyaert, I. Heyvaert, Louis Hellemans, Lieve Stockman, Frans Hennau, Chris Van Haesendonck   +5 more
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Equilibrium Capillary Forces with Atomic Force Microscopy

Physical Review Letters, 2007
We present measurements of equilibrium forces resulting from capillary condensation. The results give access to the ultralow interfacial tensions between the capillary bridge and the coexisting bulk phase. We demonstrate this with solutions of associative polymers and an aqueous mixture of gelatin and dextran, with interfacial tensions around 10 microN/
Sprakel, J.H.B., Besseling, N.A.M., Leermakers, F.A.M., Cohen Stuart, M.A.   +3 more
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Introduction to Atomic Force Microscopy

2011
Atomic force microscopy (AFM) is an invaluable tool not only to obtain high-resolution topographical images, but also to determine certain physical properties of specimens, such as their mechanical properties and composition. In addition to the wide range of applications, from materials science to biology, this technique can be operated in a number of ...
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Imaging modes of atomic force microscopy for application in molecular and cell biology.

Nature Nanotechnology, 2017
Y. Dufrêne, T. Ando, Ricardo Garcia, D. Alsteens, D. Martínez-Martín, A. Engel, C. Gerber, D. Müller   +7 more
semanticscholar   +1 more source

Atomic Force Microscopy in Nanomedicine

2006
The combination of AFM with conventional techniques, as well as AFM itself, allows answering biomedical questions of high interest. We could show this clearly for CFTR with single molecule imaging and observation of structural dynamics in native cell membranes. AFM also allows identification and determination of CFTR at single molecule level.
Andreas Ebner, Hans Oberleithner, Dessy Nikova, Hermann Schillers, Peter Hinterdorfer, Tobias Lange   +5 more
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