Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Energy dissipation in multifrequency atomic force microscopy
The instantaneous displacement, velocity and acceleration of a cantilever tip impacting onto a graphite surface are reconstructed. The total dissipated energy and the dissipated energy per cycle of each excited flexural mode during the tip interaction is
Valentina Pukhova+2 more
doaj +1 more source
Noncontact lateral-force gradient measurement on Si(111)-7×7 surface with small-amplitude off-resonance atomic force microscopy [PDF]
In this work, the authors report on a quantitative investigation of lateral-force gradient and lateral force between a tungsten tip and Si(111)-(7×7) surface using combined noncontact lateral-force microscopy and scanning tunneling microscopy ...
Atabak, Mehrdad+5 more
core +3 more sources
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler+12 more
wiley +1 more source
Repulsive bimodal atomic force microscopy on polymers
Bimodal atomic force microscopy can provide high-resolution images of polymers. In the bimodal operation mode, two eigenmodes of the cantilever are driven simultaneously.
Alexander M. Gigler+5 more
doaj +1 more source
Fast Ultrahigh-Density Writing of Low Conductivity Patterns on Semiconducting Polymers
The exceptional interest in improving the limitations of data storage, molecular electronics, and optoelectronics has promoted the development of an ever increasing number of techniques used to pattern polymers at micro and nanoscale.
di Donato, Andrea+8 more
core +1 more source
A beginner's guide to atomic force microscopy probing for cell mechanics
Atomic Force microscopy (AFM) is becoming a prevalent tool in cell biology and biomedical studies, especially those focusing on the mechanical properties of cells and tissues. The newest generation of bio‐AFMs combine ease of use and seamless integration
Núria Gavara
semanticscholar +1 more source
Probing the Nanoskyrmion Lattice on Fe/Ir(111) with Magnetic Exchange Force Microscopy [PDF]
We demonstrate that the magnetic nanoskyrmion lattice on the Fe monolayer on Ir(111) and the positions of the Fe atoms can be resolved simultaneously using magnetic exchange force microscopy. Thus, the relation between magnetic and atomic structure can be determined straightforwardly by evaluating the Fourier transformation of the real space image data.
arxiv +1 more source
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić+31 more
wiley +1 more source
Investigating Atomic Contrast in Atomic Force Microscopy and Kelvin Probe Force Microscopy on Ionic Systems using Functionalized Tips [PDF]
Noncontact atomic force microscopy (NC-AFM) and Kelvin probe force microscopy (KPFM) have become important tools for nanotechnology; however, their contrast mechanisms on the atomic scale are not entirely understood. Here we used chlorine vacancies in NaCl bilayers on Cu(111) as a model system to investigate atomic contrast as a function of applied ...
arxiv +1 more source