Results 91 to 100 of about 224,898 (299)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Laboratory Studies on Absolute n-resolved Charge-exchange Cross Sections and Modeling X-Ray Emissions for Ne8+ Colliding with H2 and He

The Astrophysical Journal
Charge exchange is a predominant process in inelastic collisions in astronomical plasmas, influencing the charge state balance and leading to X-ray emissions when solar wind ions interact with neutral gas in astrophysical environments.
P. F. Ma, H. Yin, B. Ren, T. Meng, J. Wang, Y. Wu, X. Tan, Y. Zhang, Y. Qi, K. Yao, J. Xiao, Y. Zou, B. Tu, B. Wei   +13 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Atomic physics using storage-cooler rings

, 1993
With the advent of the new generation of heavy ion storage-cooler rings brillant monochromatic beams of highly-charged ions are now available, allowing for new kinds of precision experiments in atomic physics.
Bosch, F., Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany)   +1 more
core  

Sensitivity to sterile neutrino mixing using reactor antineutrinos

European Physical Journal C: Particles and Fields, 2019
The reactor antineutrinos are used for the precise measurement of oscillation parameters in the 3-neutrino model, and also used to investigate active-sterile neutrino mixing sensitivity in the $$3+1$$ 3+1 neutrino framework. In the present work, we study
S. P. Behera, D. K. Mishra, L. M. Pant
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Early atomic models - from mechanical to quantum (1904-1913)

, 2012
A complete history of early atomic models would fill volumes, but a reasonably coherent tale of the path from mechanical atoms to the quantum can be told by focusing on the relevant work of three great contributors to atomic physics, in the critically ...
Baily, Charles, C. Baily
core   +1 more source

G0-PCC-FISH derived multi-parametric biodosimetry methodology for accidental high dose and partial body exposures

Scientific Reports
High dose radiation exposures are rare. However, medical management of such incidents is crucial due to mortality and tissue injury risks. Rapid radiation biodosimetry of high dose accidental exposures is highly challenging, considering that they usually
Usha Yadav, Nagesh N. Bhat, Utkarsha S. Mungse, Kapil B. Shirsath, Manish Joshi, Balvinder K. Sapra   +5 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source