Results 71 to 80 of about 224,898 (299)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Physics Section Progress Report

, 1955
Report discussing the progress of various projects at the Knolls Atomic Power Laboratory during the period from June to August ...
Knolls Atomic Power Laboratory
core  

Probing single biomolecules with atomic force microscopy

, 1997
Fritz J, Anselmetti D, Jarchow J, Fernandez-Busquets X. Probing single biomolecules with atomic force microscopy. Journal of structural biology. 1997;119(2):165-171.During the last years, atomic force microscopy (AFM) has developed from a microscopy tool
Fritz, Jürgen, Fernandez-Busquets, Xavier, Anselmetti, Dario ; https://orcid.org/, Jarchow, Janina   +3 more
core   +1 more source

Three-dimensional sizes and shapes of pion emission in heavy-ion collisions

European Physical Journal C: Particles and Fields
In the era of precision measurements in high-energy heavy-ion physics, there is an increasing expectation towards phenomenological and theoretical studies to provide a better description of data.
Dániel Kincses, Emese Árpási, László Kovács, Márton Nagy, Máté Csanád   +4 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Atomic Energy Commission Report AECD-3893

, 1947
A report about the development of several instruments, projects, and activities under the Physics ...
Clinton National Laboratory. Physics Division.
core  

Light-induced atomic desorption in a compact system for ultracold atoms

, 2015
This work was supported by the UK EPSRC grant GR/T08272/01 and the Leverhulme Trust Research Project Grant RPG-2013-074. G.S. acknowledges support from a SUPA Advanced Fellowship.In recent years, light-induced atomic desorption (LIAD) of alkali atoms ...
Bruce, Graham David, Cassettari, Donatella, Torralbo-Campo, Lara, Smirne, Giuseppe   +3 more
core   +1 more source

A persistent radon anomaly signal preceding the destructive 7.7 Mw earthquake in Myanmar on March 28, 2025

Scientific Reports
On March 28, 2025, a devastating earthquake doublet of moment magnitude 7.7 and 6.7 struck the Sagaing Region of Myanmar, causing extensive damage and significant casualties across Southeast Asia.
B. K. Sahoo, B. K. Sapra, Arshad Khan, M. P. Ratheesh, D. H. Kumbhar, J. J. Gaware, S. D. Kanse, Sumitra Phanjoubam, D. K. Aswal   +8 more
doaj   +1 more source

Evolution of water dynamics in the Prussian blue

EPJ Web of Conferences, 2015
Crystal water plays a crucial role towards the multifunctional properties of Prussian blue and its analogue (PBA) compounds. We have investigated the dynamics of crystal water in Prussian blue (PB), Fe(III)4[Fe(II)(CN)6]3.
Mitra S., Sharma V.K., Thakur N., Yusuf S.M., Juranyi Fanni, Mukhopadhyay R.   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source