Results 121 to 130 of about 882,221 (292)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Predicting grain boundary segregation in magnesium alloys: An atomistically informed machine learning approach

Journal of Magnesium and Alloys
Grain boundary (GB) segregation substantially influences the mechanical properties and performance of magnesium (Mg). Atomic-scale modeling, typically using ab-initio or semi-empirical approaches, has mainly focused on GB segregation at highly symmetric ...
Zhuocheng Xie, Achraf Atila, Julien Guénolé, Sandra Korte-Kerzel, Talal Al-Samman, Ulrich Kerzel   +5 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Study of the irradiation resistance and self-healing mechanism in Ti-based high-entropy metallic glass

Materials & Design
Disordered atomic arrangements in metallic glasses (MGs) can generate irregular diffusion paths and increase the diffusion distance of high-energy ions during irradiation, obstructing the diffusion channel of irradiated particles, slowing their migration,
Bingyao Liu, Wenhui He, Haoran Jiang, Jochi Tseng, Wenfei Lu, Yongkun Mu, Yuefei Jia, Yandong Jia, Bo Zhang, Kang Sun, Gang Wang   +10 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Mechanisms of boron fiber strengthening by thermal treatment [PDF]

The fracture strain for boron on tungsten fibers was studied for improvement by heat treatment under vacuum or argon environments. The mechanical basis for this improvement is thermally-induced axial contraction of the entire fiber, whereby strength ...
Dicarlo, J. A.
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Key role of excess atomic volume in structural rearrangements at the front of moving partial dislocations in copper nanocrystals. [PDF]

Sci Rep, 2019
Psakhie SG, Zolnikov KP, Kryzhevich DS, Korchuganov AV.   +3 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Magnetic field sensing based on phase Ramsey interferometry with Bose condensed 87Rb atomic gases

Shenzhen Daxue xuebao. Ligong ban
Magnetic field sensing utilizing Bose-condensed atomic gases can achieve both high sensitivity and spatial resolution. Employing two-photon transitions from F=1, mF=1→F=2, mF=-1 (F is the quantum number of total atomic angular momentum, mF is the ...
WU Jiatao, FANG Ruihuan, HAN Chengyin, MA Zhu, ZHAN Chang, LI Maojie, HUANG Jiahao, LU Bo, LEE Chaohong   +8 more
doaj   +1 more source