Results 31 to 40 of about 568 (267)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Light, humor and atoms: The physics of wine after Galilei
GalilæanaGalileo’s interest in the nature and composition of wine, summarised in the saying “wine is a compound of humour and light” that is often ascribed to him, provided the basis for the research of the subsequent generation of scientists.
Lorella Mangani
doaj +1 more source
Le Cyrano de Bergerac de Jacques Prévot
Les Dossiers du GRIHL, 2012 In his last book on Cyrano’s life and works, Jacques Prévot mainly repeats his 1977-1978 doctoral thesis. As far as biography is concerned, important components, particularly two related to religion and to the army, are ignored or underevaluated.
Madeleine Alcover
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Indonesian Journal on Learning and Advanced Education (IJOLAE)Atoms are considered entities that independently originate from human thought and perception based on a materialist perspective. In terms of the scientific model concept, Steinbuch (1977) created a scheme to indicate the epistemological process in ...
Almubarak Almubarak +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Atom-by-Atom Determination of Deuterium Atom Distribution in the Surface by Atom Probe.
SHINKU, 1998 Hydrogen is a major residual gas constituent in extremely high vacuum (XHV) and its outgassing behavior has been suggested to be closely related to its concentration and distribution in the surface layers of materials used to fabricate vacuum chambers.
ISHIKAWA, Yuichi, YOSHIMURA, Toshihiko
openaire +2 more sources
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Holism and Atomism in Tractatus Logico-Philosophicus
Analiza i Egzystencja, 2021 The aim of my paper is to describe and evaluate different conceptions of holism in Ludwig Wittgenstein’s Tractatus Logico-Philosophicus. I distinguish three readings of holistic elements in this work: i) Minimal Holism (E. Anscombe, M. Black, D.
Krystian Bogucki
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source