Results 41 to 50 of about 15,716 (302)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Indonesian Journal on Learning and Advanced Education (IJOLAE)Atoms are considered entities that independently originate from human thought and perception based on a materialist perspective. In terms of the scientific model concept, Steinbuch (1977) created a scheme to indicate the epistemological process in ...
Almubarak Almubarak +4 more
doaj +1 more source
Aristotle: Critic or Pioneer of Atomism? [PDF]
, 2007 Aristotle is typically construed as a critic of atomism. He was indeed a critic of atomism of the extreme kind formulated by Democritus, according to which bulk matter is made of nothing other than unchangeable pieces of universal matter possessing shape
Chalmers, Alan F
core
Epistemological vs. Ontological Relationalism in Quantum Mechanics: Relativism or Realism? [PDF]
, 2017 In this paper we investigate the history of relationalism and its present use in some interpretations of quantum mechanics. In the first part of this article we will provide a conceptual analysis of the relation between substantivalism, relationalism and
de Ronde, Christian +1 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Holism and Atomism in Tractatus Logico-Philosophicus
Analiza i Egzystencja, 2021 The aim of my paper is to describe and evaluate different conceptions of holism in Ludwig Wittgenstein’s Tractatus Logico-Philosophicus. I distinguish three readings of holistic elements in this work: i) Minimal Holism (E. Anscombe, M. Black, D.
Krystian Bogucki
doaj +1 more source
Why quarks cannot be fundamental particles
, 2004 Many reasons why quarks should be considered composite particles are found in the book Preons by D'Souza and Kalman. One reason not found in the book is that all the quarks except for the u quark decay. The electron and the electron neutrino do not decay.
'tHooft +9 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
, 2012 Aquinas’s Fifth Way is usually taken to be an adumbration of Paley-like design arguments. Paley-like design arguments have fallen on hard times over the past few centuries, and most contemporary defenders of design arguments in support of theism favor ...
Kronen, John, Menssen, Sandra
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source