Results 71 to 80 of about 3,060 (242)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Cumhuriyet İlahiyat Dergisi, 2018 Mehmet Bulğen’in Klasik İslâm Düşüncesinde Atomculuk Eleştirileri adlı eseri kelam, felsefe, zahirilik gibi İslam düşünce tarihinde derin etki bırakmış entelektüel geleneklere mensup düşünürlerin kelam atomculuğuna getirdikleri eleştirileri konu ...
Nazif Muhtaroğlu
doaj
Deleuze and Epicurean Philosophy: Atomic Speed and Swerve Speed
Journal of French and Francophone Philosophy, 2013 This paper reconstructs Gilles Deleuze’s interpretation of Epicurean atomism, and explicates his claim that it represents a problematic idea, similar to the idea exemplified in early, “barbaric” accounts of the differential calculus.
Michael James Bennett
doaj +1 more source
Atomic Projectiles and Their Collisions with Light Atoms [PDF]
Science, 1919 n ...
openaire +2 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Borders of a Game: Analysis of the Practical Phenomenology and Other Trends of Nowadays
Vilnius University Open Series, 2020 This article, through a prism of reduction, focuses on the gaming of practical phenomenology (M. van Manen), logical atomism (L. Wittgenstein), rhizomatic movement (Deleuze) as well as anthropocene moods in the playground of the education science.
Viktorija Voidogaitė
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Rancièrean Atomism: Clarifying the Debate between Jacques Rancière and Alain Badiou
Journal of French and Francophone Philosophy, 2015 In the late 1970s and the 1980s, a number of radical left political theorists focused their philosophical attention on the relevance of ancient atomism, revitalizing a tradition that went back to Karl Marx's work on his dissertation.
Joseph M. Spencer
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Čaro a pád logického atomizmu (Glamour and Comedown of Logical Atomism)
Ostium, 2008 This article discuss the theory presented by B. Russell and L. Wittgenstein, named logical atomism, which is one of the most interesting and fundamental theories of modern logical analysis of language.
Vladimíra Vitálošová
doaj