Results 91 to 100 of about 112,044 (333)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Conference Digest. 2000 International Quantum Electronics Conference (Cat. No.00TH8504), 2005 Atoms can be trapped and guided using nano-fabricated wires on surfaces, achieving the scales required by quantum information proposals. These Atom Chips form the basis for robust and widespread applications of cold atoms ranging from atom optics to fundamental questions in mesoscopic physics, and possibly quantum information systems.
Folman, Ron +5 more
openaire +5 more sources
LOX/Hydrogen Coaxial Injector Atomization Test Program [PDF]
Quantitative information about the atomization of injector sprays is needed to improve the accuracy of computational models that predict the performance and stability margin of liquid propellant rocket engines.
Zaller, M.
core +1 more source
Droplet size and morphology characterization for diesel sprays under atmospheric operating conditions [PDF]
, 2015 The shape of microscopic fuel droplets may differ from the perfect sphere, affecting their external surface area and thus the heat transfer with the surrounding gas.
Crua, C. +4 more
core
, 2019 Exact calculation of electronic properties of molecules is a fundamental step for intelligent and rational compounds and materials design. The intrinsically graph-like and non-vectorial nature of molecular data generates a unique and challenging machine ...
A Mauri +17 more
core +1 more source
, 2020 Correspondence Martha L. Taboada, Institute of Process Engineering in Life Sciences, Chair of Food Process Engineering, Karlsruhe Institute of Technology, Kaiserstrasse 12, 76131 Karlsruhe, Germany.
Martha L. Taboada +3 more
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Energies, 2020 Aerosol is a multiphase system, created as a result of the dispersion of a liquid in a gaseous medium. The atomized liquids are most often water and fuel; however, they can be any other substance.
Krystian Czernek +2 more
doaj +1 more source