Results 71 to 80 of about 12,570 (215)
Mini-review: air-assisted spray nozzles and applications
Frontiers in PhysicsThis mini-review summarizes the fundamental principle, spray phenomena, and atomization mechanism of air-assisted spray nozzles, and applications in various aerospace propulsion systems, agriculture irrigation, and some promising areas.
Yuanfeng Zhao +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Preparation of spherical FeSiCr powders by improved combination atomization process
Fenmo yejin jishuThe conventional combined atomization smelting process was improved and optimized in this paper, the powder morphology was improved by enhancing the effect of the primary atomization stage and prolonging the time of droplet spheroidization.
CUI Lei +5 more
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
A Study of the mechanical properties of aluminum composite materials prepared by atomization process
Iraqi Journal of Physics, 2011 Steel fiber aluminum matrix composites were prepared by atomization technique. Different air atomization conditions were considered; which were atomization pressure and distance between sample and nozzle. Tensile stress properties were studied.
Harith Ibrahim Jaffer
doaj
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Shiyou jixieThe more concentrated the droplet size after atomization, the more easily the atomization process is controlled. Adjusting atomization parameters can reduce the operating cost of the produced water system of gas field and improve the treatment effect. In
Tang Zhiwei
doaj
Old and new forms of communication between the state and society on the way to a new social contract
RUDN journal of SociologyThe article considers the concept of social contract as a consensus between the state and the people. Based on the works of T. Hobbes, D. Locke, J.-J. Rousseau, C. Montesquieu, German social thought, in the context of reflections on the “legitimacy” of R.
R. I. Anisimov
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