Results 61 to 70 of about 12,570 (215)
Effects of inclination of nozzle holes for direct injection Diesel engine on spray characteristics
Nihon Kikai Gakkai ronbunshu, 2017 This paper describes about improvement of spray characteristics of the nozzle for a direct injection Diesel nozzle, which excellent spray characteristics is obtained.
Nobushige TAMAKI, Kazuma NISHIKAWA
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
MetalsHybrid atomization represents a novel method for powder production with high cooling and crushing capacities, but previous studies have primarily focused on tin and aluminum alloy systems. In present study, FeSiBNbCu nanocrystalline powders were prepared
Huan Chen +7 more
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Nihon Kikai Gakkai ronbunshu, 2018 Reduction of particulate matter (PM) in exhaust gas from automobile engines is in high demand. Fuel stuck on the engine wall causes incomplete combustion, and generates a large amount of PM.
Kazuki YOSHIMURA +5 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Journal of Thermal Science and Technology, 2009 The purpose of this paper is to investigate the effect of the ambient pressure on the overall spray characteristics of dimethyl ether (DME) and biodiesel fuel spray in a high-pressure combustion chamber.
Hyung Jun KIM +2 more
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Characterization of the Spray of the DISI Multi-hole Injector by Means of Phase Doppler Anemometer
Journal of Thermal Science and Technology, 2010 The spray from a multi-hole injector applied to direct injection spark ignition (DISI) engine was investigated. In order to understand the detailed structure of the transient spray near the nozzle a combined LDA/PDA system was used.
Fatma AHMED +3 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source