Results 91 to 100 of about 12,070 (266)

Old and new forms of communication between the state and society on the way to a new social contract

RUDN journal of Sociology
The article considers the concept of social contract as a consensus between the state and the people. Based on the works of T. Hobbes, D. Locke, J.-J. Rousseau, C. Montesquieu, German social thought, in the context of reflections on the “legitimacy” of R.
R. I. Anisimov
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Influence of Process Parameters on the Ultrasonic Atomization Efficiency and Possibility of Testing Properties of Liquid Metals

Metrology
Over recent years, ultrasonic atomization, especially with regard to liquid metals, has become an object of increased interest, mainly from industry, for additive manufacturing, but also from investigators, for research purposes.
Rafał Szostak-Staropiętka, Wojciech Presz, Roksana Pawlic, Anna Dziubińska, Katarzyna Kołacz   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Interpreting Image Patterns for Agricultural Sprays Using Statistics and Machine Learning Techniques

Fluids
The atomization of liquid spray solutions through nozzles is a mechanism for delivering many pesticides to the target. The smallest drop sizes (
Steven Cryer, John Raymond
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Observation on application effect of vibration sieve atomizer for patients with invasive mechanical ventilation

Huli yanjiu, 2016
Objective：To observe the application effect of vibration sieve atomization method for patients with invasive mechanical ventilation.Methods：A total of 40 cases of respiratory failure patients treated by mechanical ventilation in our hospital from July ...
谷红俊, 张洁, 樊茹, 胡兴硕, 武淑萍   +4 more
doaj  

Model of atomized droplets average particle size and verification of eco-friendly hybrid lubrication (CAMQL)

Friction
In the precision cutting of difficult-to-process metals, surface thermal damage to a workpiece is a significant technical challenge. Although clean minimum quantity lubrication (MQL) technology, which replaces traditional pouring cooling, is used ...
Mingzheng Liu, Changhe Li, Dongzhou Jia, Xin Liu, Yanbin Zhang, Min Yang, Xin Cui, Teng Gao, Yusuf Suleiman Dambatta, Runze Li   +9 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source