Results 91 to 100 of about 39,209 (300)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Droplet size and morphology characterization for diesel sprays under atmospheric operating conditions [PDF]
, 2015 The shape of microscopic fuel droplets may differ from the perfect sphere, affecting their external surface area and thus the heat transfer with the surrounding gas.
Crua, C. +4 more
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Coaxial injector spray characterization using water/air as simulants [PDF]
Quantitative information about the atomization of injector sprays is required to improve the accuracy of computational models that predict the performance and stability of liquid propellant rocket engines.
Klem, Mark D., Zaller, Michelle M.
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Development of droplet entrainment and deposition models for horizontal flow
Nuclear Engineering and Technology, 2018 Models for the rate of atomization and deposition of droplets for stratified and annular flow in horizontal pipes are presented. The entrained fraction is the result of a balance between the rate of atomization of the liquid layer that is in contact with
Joshua Kim Schimpf +3 more
doaj +1 more source
Simulation of preburner sprays, volumes 1 and 2 [PDF]
The present study considered characteristics of sprays under a variety of conditions. Control of these sprays is important as the spray details can control both rocket combustion stability and efficiency.
Hardalupas, Y., Whitelaw, J. H.
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Droplet deformation and breakup in shear flow of air
, 2020 The deformation and breakup of droplets in air flows is important in many applications of spray and atomization processes. However, the shear effect of airflow has never been reported.
Che, Zhizhao, Wang, Tianyou, Xu, Zhikun
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source