Results 131 to 140 of about 18,082,934 (332)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Correlation between analytical signal and rate of sample atomization in electrothermal atomic-absorption spectrometry

, 2020
The relationship between an analytical signal, recorded at the spectrophotometer output, and the rate of sample atomization in the furnace has been analysed theoretically. The atomic transfer in the gas phase and the time constant of the recording system
Shlyakhtina O., Gilmutdinov A.
core  

Diesel spray atomization model considering nozzle exit turbulence conditions

, 2019
Art atomization model for plain-orifice diesel fuel sprays is developed. It considers both turbulent fluctuation in the jet flow and wave growth by gas inertia force due to the jet velocity. The atomization model developed is implemented as a module into
Koo, JY, Lee, EJ, Huh, KY
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Impact of atomizing medium on the characteristics of high-vanadium steel powder: A comparative study of nitrogen and argon

Journal of Materials Research and Technology
In this study, the impact of different atomizing media on the morphology, phase and cooling rate of high-vanadium steel powder particles was investigated.
Yaxian Shi, Xinggang Li, Peng Wang, Yudong Liang, Changchun Ge   +4 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Improvement of Phenol Degradation by UV Irradiation on Ultrasonic Atomized Droplets

Chemical Engineering Transactions
Photocatalysis such as TiO2 particles are expected to be applied to the degradation of hazardous organic materials as an advanced oxidation processes (AOPs).
Daisuke Kobayashi, Hinano Watanabe
doaj  

Atomization of a G-DI spray with air dissolved in gasoline and mono-component fuels [PDF]

, 2019
A spray from a GDI multi-hole injector is used to investigate and compare the atomization results from different fuels in which air has been dissolved to promote the atomization.
R. Dondè, L. Araneo
core