Results 91 to 100 of about 1,672,341 (295)

Answer Sets for Logic Programs with Arbitrary Abstract Constraint Atoms

open access: yes, 2011
In this paper, we present two alternative approaches to defining answer sets for logic programs with arbitrary types of abstract constraint atoms (c-atoms).
Pontelli, E., Son, T. C., Tu, P. H.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Towards negative index self-assembled metamaterials

open access: yes, 2014
We investigate the magnetic response of meta-atoms that can be fabricated by a bottom-up technique. Usually such meta-atoms consist of a dielectric core surrounded by a large number of solid metallic nanoparticles.
Fruhnert, Martin   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A compact design for a magnetic synchrotron to store beams of hydrogen atoms

open access: yes, 2015
We present a design for an atomic synchrotron consisting of 40 hybrid magnetic hexapole lenses arranged in a circle. We show that for realistic parameters, hydrogen atoms with a velocity up to 600 m/s can be stored in a 1-meter diameter ring, which ...
Bethlem, Hendrick L   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Quantum Transport of Bosonic Cold Atoms in Double Well Optical Lattices

open access: yes, 2011
We numerically investigate, using the time evolving block decimation algorithm, the quantum transport of ultra-cold bosonic atoms in a double well optical lattice through slow and periodic modulation of the lattice parameters (intra- and inter-well ...
Gong, Ming   +2 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Quantum phases of a Feshbach-resonant atomic Bose gas in one dimension

open access: yes, 2005
We study an atomic Bose gas with an s-wave Feshbach resonance in a one-dimensional optical lattice, with the densities of atoms and molecules incommensurate with the lattice.
O. A. Starykh   +3 more
core   +1 more source

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