Results 71 to 80 of about 1,672,341 (295)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Insights into Components of Prospective Science Teachers’ Mental Models and Their Preferred Visual Representations of Atoms

Education Sciences, 2019
This study focused on determining the elements of mental models of atomic structure and views on visual representations of models of atomic structure in two sub-cohorts of student teachers studying at a university in Turkey.
Aysegül Derman, Nuriye Koçak, Ingo Eilks   +2 more
doaj   +1 more source

Three-Component Fermionic Atoms with Repulsive Interaction in Optical Lattices

, 2010
We investigate three-component (colors) repulsive fermionic atoms in optical lattices using the dynamical mean field theory. Depending on the anisotropy of the repulsive interactions, either a color density-wave state or a color selective staggered state
Inaba, Kensuke, Miyatake, Shin-ya, Suga, Sei-ichiro   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Suppressing dipolar relaxation in thin layers of dysprosium atoms

Nature Communications
The dipolar interaction can be attractive or repulsive, depending on the position and orientation of the dipoles. Constraining atoms to a plane with their magnetic moment aligned perpendicularly leads to a largely side-by-side repulsion and generates a ...
Pierre Barral, Michael Cantara, Li Du, William Lunden, Julius de Hond, Alan O. Jamison, Wolfgang Ketterle   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

One-dimensional array of ion chains coupled to an optical cavity

New Journal of Physics, 2013
We present a novel system where an optical cavity is integrated with a microfabricated planar-electrode ion trap. The trap electrodes produce a tunable periodic potential allowing the trapping of up to 50 separate ion chains aligned with the cavity and ...
Marko Cetina, Alexei Bylinskii, Leon Karpa, Dorian Gangloff, Kristin M Beck, Yufei Ge, Matthias Scholz, Andrew T Grier, Isaac Chuang, Vladan Vuletić   +9 more
doaj   +1 more source

Improvement of the NIFS Atom and Molecular Database

Atoms, 2019
The NIFS (National Institute for Fusion Science) Atom and Molecular Database, which has been available online since 1997, is a numerical atomic and molecular database of collision processes that is important for fusion research.
Masahiko Emoto, Izumi Murakami, Daiji Kato, Masanobu Yoshida, Masatoshi Kato, Setsuo Imazu   +5 more
doaj   +1 more source

Conflicting Demands of Chemistry and Inclusive Teaching—A Video-Based Case Study

Education Sciences, 2020
Almost every country in the world is obligated to implement education policies to enable an inclusive school system. However, implementing techniques to be inclusive in schools is a major challenge to teachers, especially to those teaching a subject at ...
Simone Abels, Brigitte Koliander, Thomas Plotz   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source