Results 51 to 60 of about 1,672,341 (295)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Buffer gas loaded magneto-optical traps for Yb, Tm, Er and Ho
Direct loading of lanthanide atoms into magneto-optical traps (MOTs) from a very slow cryogenic buffer gas beam source is achieved, without the need for laser slowing. The beam source has an average forward velocity of 60– $70\;{\rm m}\;{{{\rm s}}^{-1}}$
Boerge Hemmerling +4 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Superfluid state of repulsively interacting three-component fermionic atoms in optical lattices
We investigate the superfluid state of repulsively interacting three-component (color) fermionic atoms in optical lattices. When the anisotropy of the three repulsive interactions is strong, atoms of two of the three colors form Cooper pairs and atoms of
D. J. Scalapino +2 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Blockchain Design for an Embedded System
This paper proposes a blockchain-based mapping protocol for distributed robotic systems running on embedded hardware. This protocol was developed for a robotic system designed to locomote on lattice structures for space applications.
Sara Falcone +3 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Location of Al and Si atoms in substituted boron carbide
Boron carbide is a material of interest for personal body armor, but its low fracture toughness and amorphization limits its widespread use. Al and Si atoms in doped boron carbide reduce this problem.
V. V. Garbuz +10 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Thermodynamic metal melting bases. Foundry production and metallurgy
Based on thermodynamic calculations, it is shown that metal melting is an equilibrium process that occurs at a constant temperature. In melting, microcrystals mainly disintegrate into nanocrystals.
E. I. Marukovich, V. Yu. Stetsenko
doaj +1 more source

