Results 91 to 100 of about 348,699 (383)

Economic evidence for the prevention and treatment of atopic eczema: a protocol for a systematic review [PDF]

open access: yes, 2016
Background: Eczema, synonymous with atopic eczema or atopic dermatitis, is a chronic skin disease that has a similar impact on health-related quality of life as other chronic diseases.
AS Paller   +18 more
core   +1 more source

Assessment of the severity of atopic dermatitis

open access: yesPrzegląd Dermatologiczny, 2016
Atopic dermatitis is a frequent, chronic and recurrent inflammatory skin disease with complex etiology. Typical symptoms of this disease are persistent itching and dry skin.
Agnieszka Bożek, Adam Reich
doaj   +1 more source

Ten-Year trends and prevalence of asthma, allergic rhinitis, and atopic dermatitis among the Korean population, 2008–2017

open access: yesClinical and experimental pediatrics, 2020
Background Major questions remain regarding the age-stratified trends of allergic diseases and asthma in Korea. Purpose To identify the estimated recent prevalence and 10-year trends in asthma, allergic rhinitis, and atopic dermatitis among the Korean ...
Jihyun Ha, Seung Won Lee, D. Yon
semanticscholar   +1 more source

Cinobufagin Directly Targets PDE4D to Disrupt Fibroblast–Dendritic Cell Crosstalk in Atopic Dermatitis

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing revealed that MIF signaling drives inflammatory fibroblastmyeloid cell crosstalk in atopic dermatitis. Cinobufagin, a potent PDE4D inhibitor, suppresses MIF and reduces inflammation by restoring the cAMP/PKA/CREB pathway. Genetic knockout validates PDE4D as a key driver and promising therapeutic target for atopic dermatitis ...
Shicong Li   +14 more
wiley   +1 more source

Emerging Topical and Systemic JAK Inhibitors in Dermatology [PDF]

open access: yes, 2019
Accumulating data on cellular and molecular pathways help to develop novel therapeutic strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic dermatitis, two clinically and immunologically well-defined disorders.
Ghoreschi, Kamran   +2 more
core   +1 more source

Pathophysiology of atopic dermatitis: Clinical implications.

open access: yesAllergy and Asthma Proceedings, 2019
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Genetic predisposition, epidermal barrier disruption, and dysregulation of the immune system are some of the critical components of AD.
Jihyun Kim, B. Kim, D. Leung
semanticscholar   +1 more source

Counting the Burden: Atopic Dermatitis and Health-related Quality of Life

open access: yesActa Dermato-Venereologica, 2020
Atopic dermatitis is the most prevalent chronic inflammatory skin condition globally. The burden of atopic dermatitis on children and adults is extensive and there is also significant impact on the lives of patient caregivers and family members.
Faraz M. Ali, J. Vyas, A. Finlay
semanticscholar   +1 more source

A Multicenter Validation of a Fully Automated Chemiluminescence Immunoassay for Plasma Elafin in Psoriasis Diagnosis and Severity Assessment

open access: yesAdvanced Science, EarlyView.
The fully automated CLIA demonstrates high sensitivity and specificity for plasma Elafin, achieving 88% diagnostic accuracy and an AUC of 0.92 for psoriasis detection in a multicenter cohort. The assay reliably distinguishes psoriasis from other dermatoses, objectively stratifies disease severity, and allows longitudinal monitoring, supporting its ...
Jingkun Yi   +8 more
wiley   +1 more source

The microbiome in patients with atopic dermatitis. [PDF]

open access: yes, 2019
As an interface with the environment, the skin is a complex ecosystem colonized by many microorganisms that coexist in an established balance. The cutaneous microbiome inhibits colonization with pathogens, such as Staphylococcus aureus, and is a crucial ...
Gallo, Richard L   +7 more
core  

Antimicrobial peptides: agents of border protection for companion animals. [PDF]

open access: yes, 2012
Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K   +2 more
core   +1 more source

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