Results 111 to 120 of about 348,699 (383)

Early probiotic supplementation for the prevention of atopic disease in newborns-probiotics and the hygiene hypothesis-. [PDF]

, 2011
Environmental factors during early infancy could theoretically affect immune system development and subsequent risk of allergic disease. One potentially helpful exposure is early infant supplementation with specific probiotic strains.
Cabana, Michael D
core   +3 more sources

Improvement of quality of life in patients with concomitant allergic asthma and atopic dermatitis: one year follow-up of omalizumab therapy

European Journal of Medical Research, 2011
Objective Anti IgE treatment with omalizumab is efficacious in the treatment of patients suffering from allergic asthma, improving asthma control and improving quality of life.
Velling P, Skowasch D, Pabst S, Jansen E, Tuleta I, Grohé C   +5 more
doaj   +1 more source

Characterizing local and systemic exposure to clobetasol propionate in healthy subjects and patients with atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims There is a potential risk of systemic side‐effects with the use of potent corticosteroids, such as clobetasol propionate (CP). This concern is of particular interest in paediatric patients. The aim of this study was to develop and verify a physiologically based pharmacokinetic (PBPK) model to describe the local and systemic exposure to CP
Janna K. Duong, Sven van Dijkman, Gary Ong, Alexandra Marta, Adriana Ceci, Ernesto Bonifazi, Oscar Della Pasqua   +6 more
wiley   +1 more source

Epidemiology of atopic dermatitis in adults: Results from an international survey

Allergy. European Journal of Allergy and Clinical Immunology, 2018
There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD).
S. Barbarot, S. Auzière, A. Gadkari, G. Girolomoni, L. Puig, E. Simpson, D. Margolis, M. Bruin-Weller, L. Eckert   +8 more
semanticscholar   +1 more source

Profiling a Neo‐Antigen‐Driven Immune Response in Healthy Volunteers: A Randomized, Double‐Blind, Placebo‐Controlled Study of the KLH Challenge Model

Clinical Pharmacology &Therapeutics, EarlyView.
Novel compounds targeting the adaptive immune system are commonly initially investigated in healthy volunteers (HV). HV frequently lack constitutively expressed drug‐target engagement biomarkers, complicating the evaluation of pharmacological activity. The keyhole limpet hemocyanin (KLH) neo‐antigen challenge elicits a controlled immune response in HV ...
Micha N. Ronner, Hendrika W. Grievink, Mahdi Saghari, Michelle Osse, Thierry P.P. van den Bosch, Jeffrey Damman, Marieke L. de Kam, Jacobus Burggraaf, Naomi B. Klarenbeek, Manon A. A. Jansen, Matthijs Moerland   +10 more
wiley   +1 more source

Lack of Association Between Toll-like Receptor 2 Polymorphisms (R753Q and A-16934T) and Atopic Dermatitis in Children from Thrace Region of Turkey

Balkan Medical Journal, 2017
Background: Atopic dermatitis is the most common chronic inflammatory skin disease. A complex interaction of both genetic and environmental factors is thought to contribute to the disease. Aims: To evaluate whether single nucleotide polymorphisms in the
Ceren Can, Mehtap Yazıcıoğlu, Hakan Gürkan, Hilmi Tozkır, Adnan Görgülü, Necdet Hilmi Süt   +5 more
doaj   +1 more source

Genetic and Epigenetic Aspects of Atopic Dermatitis

International Journal of Molecular Sciences, 2020
Atopic dermatitis is a heterogeneous disease, in which the pathogenesis is associated with mutations in genes encoding epidermal structural proteins, barrier enzymes, and their inhibitors; the role of genes regulating innate and adaptive immune responses
B. Nedoszytko, E. Reszka, D. Gutowska-Owsiak, M. Trzeciak, M. Lange, J. Jarczak, M. Niedoszytko, E. Jabłońska, J. Romantowski, Dominik Strapagiel, J. Skokowski, Anna Siekierzycka, R. Nowicki, I. Dobrucki, A. Zaryczańska, L. Kalinowski   +15 more
semanticscholar   +1 more source

Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model

Barrier Immunity, EarlyView.
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia, Mathias Hochgerner, Qingzhen Wei, Xian'ge Zhong, Jiucun Wang   +4 more
wiley   +1 more source

Management of Children with Atopic Dermatitis: A Narrative Review

Journal of Pediatrics Review, 2017
Context: Atopic dermatitis is a chronic, relapsing skin disorder that affects all ages including infancy and childhood. There are many proved and unproved treatments for atopic dermatitis.
Masoud Golpour, Javad Ghaffari, Abbas Dabbaghzadeh, Javad Rezaiefard   +3 more
doaj  

PEMBERSIHAN LUKA DERMATITIS ATOPIK DENGAN CAIRAN NORMAL SALIN

Jurnal Keperawatan, 2014
PEMBERSIHAN LUKA DERMATITIS ATOPIK DENGAN CAIRAN NORMAL SALIN (Atopic Dermatitis Wound Cleaning with Normal Saline) Tavip Dwi Wahyuni Poltekkes Kemenkes Malang e-mail: dwitavip@yahoo.com ABSTRAK Dermatitis atopik merupakan penyakit peradangan ...
Tavip Dwi Wahyuni
doaj   +1 more source