Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment
Advanced NanoBiomed Research, EarlyView.Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang +7 more
wiley +1 more source
Measurement properties of quality of life measurement instruments for infants, children and adolescents with eczema: protocol for a systematic review [PDF]
, 2016 Background: Eczema is a common chronic or chronically relapsing skin disease that has a substantial impact on quality of life (QoL). By means of a consensus-based process, the Harmonising Outcome Measures in Eczema (HOME) initiative has identified QoL as
AD Furlan +23 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Magnitude of atopic dermatitis and associated factors among children in northwest Ethiopia
Scientific ReportsAtopic dermatitis is a chronic inflammatory skin disease that typically begins in infancy and extends into adulthood in a small proportion of cases. Around 20% of children and 5% of adults worldwide suffer from atopic dermatitis.
Alemu Bezabih Tegegnie +4 more
doaj +1 more source
The measurement of health-related quality of life (QOL) in paediatric clinical trials: a systematic review [PDF]
, 2004 Background The goal of much care in chronic childhood illness is to improve quality of life (QOL). However, surveys suggest QOL measures are not routinely included.
Clarke, S., Eiser, C.
core +3 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet +17 more
wiley +1 more source
Filaggrin loss-of-function mutations and atopic dermatitis as risk factors for hand eczema in apprentice nurses:part II of a prospective cohort study [PDF]
, 2013 BACKGROUND/OBJECTIVES: Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet ...
Bakker, Jan G. +8 more
core +2 more sources
Investigating the Ligand‐Binding Properties of N‐arylbenzimidazoles as Novel Elastase Inhibitors
ChemMedChem, EarlyView.A series of novel N‐[(3,5‐dimethylphenyl)methyl]‐1H‐benzimidazole derivatives is designed, synthesized, and evaluated for inhibitory activity against elastase. Several compounds demonstrate an antielastase activity, including the N‐(2‐bromophenyl)‐2‐(6‐chloro‐1‐(3,5‐dimethylbenzyl)‐1H‐benzo[d]imidazol‐2‐ylthio)acetamide, showing the greatest potency ...
Giovanna Pitasi +6 more
wiley +1 more source
The Impact of Atopic Dermatitis on Sexual Function and Reproductive Desires in Women
Acta Dermato-VenereologicaAtopic dermatitis is a prevalent skin condition that affects up to 17% of adult population. It can lead to itching, pain, and other symptoms such as sleep disturbance, anxiety, and depression.
Juan-Angel Rodríguez-Pozo +6 more
doaj +1 more source
The influence of atopic dermatitis on the quality of life of children [PDF]
, 2016 The aim: to analyze psychosocial aspects based on a comprehensive assessment of determine the quality of life parameters in families where a child suffers from atopic dermatitis. Materials and Methods.
Romaniuk, Oksana Kostiantynivna +3 more
core