Results 121 to 130 of about 338,947 (383)

Crisaborole Ointment Improves Quality of Life of Patients with Mild to Moderate Atopic Dermatitis and Their Families. [PDF]

, 2018
IntroductionThe impact of crisaborole ointment, a nonsteroidal phosphodiesterase 4 inhibitor for the treatment of mild to moderate atopic dermatitis (AD), on quality of life (QoL) was assessed in two identically designed phase 3 studies (AD-301 ...
Boguniewicz, Mark, Chamlin, Sarah L, Eichenfield, Lawrence F, Feldman, Steven R, Paller, Amy S, Silverberg, Jonathan I, Simpson, Eric L, Zane, Lee T   +7 more
core   +2 more sources

Exploring Regulatory Frameworks for Exosome Therapy: Insights and Perspectives

Health Care Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) have emerged as a promising technology for diagnostic and therapeutic applications in clinical settings over the past decade. However, their advancement is hindered by complex technological and regulatory challenges.
Qiushi Li, Yuxia Li, Jiaqing Shao, Jianhua Sun, Lan Hu, Xia Yun, Chen Liuqing, Likun Gong, Shuxia Wu   +8 more
wiley   +1 more source

By protecting against cutaneous inflammation, epidermal pigmentation provided an additional advantage for ancestral humans. [PDF]

, 2019
Pigmentation evolved in ancestral humans to protect against toxic, ultraviolet B irradiation, but the question remains: "what is being protected?" Because humans with dark pigmentation display a suite of superior epidermal functions in comparison with ...
Abuabara, Katrina, Elias, Peter M, Lee, Chih-Hung, Lin, Tzu-Kai, Man, Mao-Qiang, Sheu, Hamm-Ming, Tsai, Jui-Chen, Wakefield, Joan S   +7 more
core   +1 more source

Emerging Methods to Objectively Assess Pruritus in Atopic Dermatitis. [PDF]

, 2019
INTRODUCTION:Atopic dermatitis (AD) is an inflammatory skin disease with a chronic, relapsing course. Clinical features of AD vary by age, duration, and severity but can include papules, vesicles, erythema, exudate, xerosis, scaling, and lichenification.
Bhutani, Tina, Liao, Wilson, Ly, Karen, Smith, Mary Patricia, Thibodeaux, Quinn, Weerasinghe, Thulasi, Wu, Jashin J, Yosipovitch, Gil   +7 more
core   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Atopic dermatitis, cutaneous steroids and cataracts in children: two case reports

Journal of Medical Case Reports, 2008
Introduction Atopic dermatitis is a chronic, pruritic, eczematous skin disease mediated through an immediate (type I) hypersensitivity reaction. Posterior sub-capsular cataracts are a recognised complication of atopic dermatitis in adults; however they ...
Tatham Andrew
doaj   +1 more source

Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]

, 2019
Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna), Shadrin, O. (Oleg)   +1 more
core   +3 more sources

PEG‐Free Nanoemulsions With Alkyl Polyglucoside and Baccharis dracunculifolia Essential Oil: Physicochemical Behavior, pH Dependence and Skin Repair Properties

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT Alkyl polyglucosides (APG) are biodegradable, non‐ionic surfactants from renewable sources with low ecotoxicity. This study developed a novel PEG‐free nanoemulsion (NE) using APG to encapsulate Baccharis dracunculifolia essential oil (BDO) for skin repair.
Carolina Sousa Ponciano, Fernanda Brito Leite, Carine Cassimiro Cedrola, Julliana da Fonseca Alves, Ana Cláudia Chagas de Paula, Luiz Fernando Cappa de Oliveira, Thais Nogueira Barradas, Fernanda Maria Pinto Vilela   +7 more
wiley   +1 more source

Update on Atopic Dermatitis

Acta Médica Portuguesa, 2019
With an increasing prevalence during the past decades, atopic dermatitis has become a global health issue. A literature search following a targeted approach was undertaken to perform this non-systematic review, which intends to provide an overview of the epidemiology, pathophysiology, clinical features, comorbidities, and current therapies for the ...
Torres, Tiago, Ferreira, Eduarda Osório, Gonçalo, Margarida, Mendes-Bastos, Pedro, Selores, Manuela, Filipe, Paulo   +5 more
openaire   +6 more sources

TREatment of ATopic eczema (TREAT) Registry Taskforce: consensus on how and when to measure the core dataset for atopic eczema treatment research registries. [PDF]

, 2019
BackgroundComparative, real-life and long-term evidence on the effectiveness and safety of phototherapy and systemic therapy in moderate-to-severe atopic eczema (AE) is limited.
Apfelbacher, CJ, Arents, BWM, Barbarot, S, Bosma, AL, Deleuran, M, Eichenfield, LF, Flohr, C, Gerbens, LAA, International TREAT Registry Taskforce, Irvine, AD, Manca, A, Middelkamp-Hup, MA, Schmitt, J, Spuls, PI, Vermeulen, FM, Vestergaard, C, Wall, D, Weidinger, S   +17 more
core