Results 151 to 160 of about 338,947 (383)
Targeting JAK‐1 in Disseminated Cutaneous Lichen Planus
ABSTRACT We report the case of a 63‐year‐old woman with an exuberant and recalcitrant clinical presentation of LP who had an excellent response to 200 mg/day abrocitinib, a JAK‐1 inhibitor, after failure to other commonly used therapies. The efficacy of JAK inhibitors in lichen planus is supported by small case series and isolated case reports. Further
F. Barbosa, L. Siems, D. Luz, A. Duarte
wiley +1 more source
ABSTRACT Background Patients with dermatological immune mediated inflammatory diseases (IMIDs) are increasingly treated with immunosuppressive and ‐modulating drugs. Some of these drugs increase the risk of acquiring infections and more complications can arise during an infection while treated with these agents.
Femke Lieten+8 more
wiley +1 more source
Shrinkage estimation for dose-response modeling in phase II trials with multiple schedules
Recently, phase II trials with multiple schedules (frequency of administrations) have become more popular, for instance in the development of treatments for atopic dermatitis.
Friede, Tim+2 more
core +1 more source
Background Atopic dermatitis is one of the most common skin disorders. Evidence has suggested an association between skin disorders, such as atopic dermatitis, and Parkinson's disease (PD).
Taofeng Zhou+5 more
doaj +1 more source
ABSTRACT Background Wildfire air pollution causes many adverse environmental and health effects, including adverse skin reactions. However, whether wildfire‐associated air pollution and psoriasis disease activity are associated remains unknown. Objectives To examine the association between short‐term exposure to air pollution from wildfires and rates ...
Johan Anker Chrom Allerup+5 more
wiley +1 more source
Modern treatment methods in atopic dermatitis - literature overview
Introduction and aim: Atopic dermatitis (AD) is a chronic inflammatory skin disease. It is characterised by periods of exacerbation and remission of symptoms such as pruritus, dry skin and eczematous lesions with characteristic morphology.
Martyna Borowska-Łygan+6 more
doaj +1 more source
Twenty‐seven young patients, mostly females, presenting with monomorphous, discrete, tiny, superficial follicular pustules on the face (44.4%), the face and neck (51.8%) and the neck (3.7%). The eruption was itchy in 44.4%, recurrent in 81% of cases and responded well to topical corticosteroids. Histopathologic findings of 3 cases revealed infundibular
Hui‐Peng Huang+4 more
wiley +1 more source
ABSTRACT The treatment landscape for moderate‐to‐severe atopic dermatitis (AD) has evolved significantly with the introduction of novel targeted therapies addressing specific pathogenic mechanisms of the disease. Despite this therapeutic revolution, a proportion of patients experience intolerance and/or inadequate response to multiple lines of ...
Elena Ippoliti+5 more
wiley +1 more source
Pilot Study of Tildrakizumab in the Treatment of Stable Non‐Segmental Vitiligo
ABSTRACT Background Treatment for vitiligo is limited, with variable efficacy, and can be time‐consuming or expensive. Recent developments within biologic therapy have demonstrated promising results with managing chronic autoimmune conditions. Objectives To evaluate the efficacy of tildrakizumab in inducing repigmentation in vitiligo.
Henry Lee+13 more
wiley +1 more source