Results 41 to 50 of about 69,766 (243)

Ultraviolet index: a light in atopic dermatitis and vitamin D research? [PDF]

Anais Brasileiros de Dermatologia, 2016
BACKGROUND: The role played by vitamin D in atopic dermatitis is controversial and has been the focus of many studies. The ultraviolet index has not been considered in this type of research.
Kleyton de Carvalho Mesquita, Ana Carolina de Souza Machado Igreja, Izelda Maria Carvalho Costa   +2 more
doaj   +1 more source

The relationship between atopic dermatitis and atopic itch in children and the psychosocial functioning of their mothers: A cross-sectional study

Frontiers in Medicine, 2023
Atopic dermatitis is a chronic inflammatory skin disease significantly affecting patients’ and their parents’ lives. Mothers are mostly responsible for the long-term treatment and their wellbeing is essential.
Aleksandra K. Kobusiewicz, Aleksandra K. Kobusiewicz, Bartlomiej Tarkowski, Andrzej Kaszuba, Aleksandra Lesiak, Joanna Narbutt, Anna Zalewska-Janowska   +6 more
doaj   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Eco-Friendly Synthesis of Silver Nanoparticles Using Sapindus mukorossi Extract With Antibacterial and Photocatalytic Activities

Scientifica
Green synthesis of silver nanoparticles (AgNPs) offers an eco-friendly approach for developing multifunctional nanomaterials. In this study, AgNPs were synthesized using Sapindus mukorossi fruit extract as both reducing and stabilizing agents. UV–visible
Mohit Chand, Han-Chen Ho, Chia-Jyi Liu, Chih-Wei Chang, Higuchi Kazuki, Jui-Yu Chou   +5 more
doaj   +1 more source

Improvement of quality of life in patients with concomitant allergic asthma and atopic dermatitis: one year follow-up of omalizumab therapy

European Journal of Medical Research, 2011
Objective Anti IgE treatment with omalizumab is efficacious in the treatment of patients suffering from allergic asthma, improving asthma control and improving quality of life.
Velling P, Skowasch D, Pabst S, Jansen E, Tuleta I, Grohé C   +5 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis

Nature Communications
Atopic dermatitis is a highly heritable and common inflammatory skin condition affecting children and adults worldwide. Multi-ancestry approaches to atopic dermatitis genetic association studies are poised to boost power to detect genetic signal and ...
Meritxell Oliva, Mrinal K. Sarkar, Michael E. March, Amir Hossein Saeidian, Frank D. Mentch, Chen-Lin Hsieh, Fanying Tang, Ranjitha Uppala, Matthew T. Patrick, Qinmengge Li, Rachael Bogle, J. Michelle Kahlenberg, Deborah Watson, Joseph T. Glessner, Leila Youssefian, Hassan Vahidnezhad, Lam C. Tsoi, Hakon Hakonarson, Johann E. Gudjonsson, Kathleen M. Smith, Bridget Riley-Gillis   +20 more
doaj   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source