Results 31 to 40 of about 2,229 (169)

Long-term outcomes of 0.1% tacrolimus eye drops in eyes with severe allergic conjunctival diseases

Allergy, Asthma & Clinical Immunology, 2021
Background Because atopic dermatitis does not heal completely, associated severe atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC) often require long-term treatment.
Hiroyuki Yazu, Kazumi Fukagawa, Eisuke Shimizu, Yasunori Sato, Hiroshi Fujishima   +4 more
doaj   +1 more source

A Case of Refractory Vernal Keratoconjunctivitis Showing Improvement after the Administration of Upadacitinib for the Treatment of Atopic Dermatitis

Diagnostics
Vernal keratoconjunctivitis is a persistent allergic ocular disease predominantly mediated by the T-helper 2 lymphocyte-associated immune response. The standard therapeutic approaches for vernal keratoconjunctivitis include topical corticosteroids and ...
Yoshihito Mima, Eri Tsutsumi, Tsutomu Ohtsuka, Ippei Ebato, Yukihiro Nakata, Taro Kubota, Yuta Norimatsu   +6 more
doaj   +1 more source

Diagnostic criteria of chronic conjunctivitis: atopic keratoconjunctivitis and vernal keratoconjunctivitis

Current Opinion in Allergy & Clinical Immunology, 2023
Purpose of review Chronic ocular allergies, vernal (VKC) and atopic keratoconjunctivitis (AKC) are relatively rare conditions that require definite diagnostic criteria to the most appropriate therapeutical approach. Recent findings The diagnosis of both VKC and AKC is generally ...
Leonardi, Andrea, Righetti, Giuseppe, Giovannini, Giulia, De Marchi, Vittorio, Occhiuto, Matteo   +4 more
openaire   +3 more sources

Positive regulation of innate immune response by miRNA-let-7a-5p

Frontiers in Genetics, 2023
Background: We have hypothesized that different factors are involved in the severity of ACD and AD because some but not all patients with atopic dermatitis (AD) present with allergic conjunctival disease (ACD) including severe types such as atopic ...
Mayumi Ueta, Hiromi Nishigaki, Seitaro Komai, Katsura Mizushima, Risa Tamagawa-Mineoka, Yuji Naito, Norito Katoh, Chie Sotozono, Shigeru Kinoshita   +8 more
doaj   +1 more source

Japanese Guideline for Allergic Conjunctival Diseases

Allergology International, 2011
The definition, classification, pathogenesis, test methods, clinical findings, criteria for diagnosis, and therapies of allergic conjunctival disease are summarized based on the Guidelines for Clinical Management of Allergic Conjunctival Disease (Second ...
Etsuko Takamura, Eiichi Uchio, Nobuyuki Ebihara, Shigeaki Ohno, Yuichi Ohashi, Shigeki Okamoto, Naoki Kumagai, Yoshiyuki Satake, Jun Shoji, Yayoi Nakagawa, Kenichi Namba, Kazumi Fukagawa, Atsuki Fukushima, Hiroshi Fujishima   +13 more
doaj   +1 more source

Incorporating the Competencies of Evidence‐Based Veterinary Medicine Focused on Pharmacotherapeutics Into Clinical Rotations for Small Animal Dermatology and Food Animal Medicine and Surgery at a Veterinary Medical Teaching Hospital in the US

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Building the skills and knowledge necessary to practice evidence‐based veterinary medicine (EBVM) should occur throughout the veterinary curriculum. Operationalizing EBVM includes asking a clinical question in PICO format, searching the biomedical literature for evidence, critically appraising the evidence, and applying the evidence to make a ...
Virginia R. Fajt, Adam P. Patterson, Dusty Nagy, Jennifer Schleining, Kevin Washburn   +4 more
wiley   +1 more source

Japanese guidelines for allergic conjunctival diseases 2017

Allergology International, 2017
The definition, classification, pathogenesis, test methods, clinical findings, criteria for diagnosis, and therapies of allergic conjunctival disease are summarized based on the Guidelines for Clinical Management of Allergic Conjunctival Disease (Second ...
Etsuko Takamura, Eiichi Uchio, Nobuyuki Ebihara, Shigeaki Ohno, Yuichi Ohashi, Shigeki Okamoto, Naoki Kumagai, Yoshiyuki Satake, Jun Shoji, Yayoi Nakagawa, Kenichi Namba, Kazumi Fukagawa, Atsuki Fukushima, Hiroshi Fujishima   +13 more
doaj   +1 more source

Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal, Roshanay Ejaz Awan, Hur Abbas, Zahra Sania, Ashna Habib, Syeda Kaneez Sakina, Amina Mahmud, Mohammed Mahmmoud Fadelallah Eljack   +7 more
wiley   +1 more source

Ocular surface disease in atopic dermatitis

Acta Ophthalmologica, Volume 104, Issue S291, Page S4-S28, June 2026.
ENGLISH SUMMARY Atopic keratoconjunctivitis (AKC) is a severe ocular surface disease (OSD) that significantly affects patients' quality of life and can lead to blindness. AKC is associated with atopic dermatitis (AD), a common chronic inflammatory skin disease affecting both children and adults.
Pernille May Hansen
wiley   +1 more source

Benralizumab for anti‐tumor necrosis factor‐associated eosinophilic gastrointestinal disease in a child with ileal Crohn's: A case report

JPGN Reports, Volume 7, Issue 2, Page 312-314, May 2026.
Abstract Crohn's disease (CD) and eosinophilic gastrointestinal diseases (EGIDs) are distinct inflammatory entities, but eosinophilic disease may emerge as a paradoxical immune complication of anti–tumor necrosis factor therapy. We report a 12‐year‐old boy with terminal ileal CD who developed severe eosinophilic gastritis and ileitis, peripheral ...
Jonathan Dudzik, Alberto Pinzon‐Charry, Peter Lewindon, Fariha Balouch   +3 more
wiley   +1 more source