Results 91 to 100 of about 59,745 (273)

Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development

Clinical and Developmental Immunology, 2012
Asthma is a hereditary disease associated with IgE-mediated reaction. Whether maternal atopy and paternal atopy have different impacts on perinatal IgE production and asthma development remains unclear.
Chih-Chiang Wu, Rong-Fu Chen, Ho-Chang Kuo   +2 more
doaj   +1 more source

Association of early viral lower respiratory infections and subsequent development of atopy, a systematic review and meta-analysis of cohort studies.

PLoS ONE, 2020
IntroductionExisting evidence on the relationship between childhood lower respiratory tract infections (LRTI) and the subsequent atopy development is controversial. We aimed to investigate an association between viral LRTI at 2 years.MethodsWe conducted
Sebastien Kenmoe, Cyprien Kengne-Nde, Abdou Fatawou Modiyinji, Jean Joel Bigna, Richard Njouom   +4 more
doaj   +1 more source

Do early-life exposures explain why more advantaged children get eczema? Findings from the U.K. Millennium Cohort Study [PDF]

, 2015
Background: Atopic dermatitis (eczema) in childhood is socially patterned, with higher incidence in more advantaged populations. However, it is unclear what factors explain the social differences.
Hope, S., Law, C., Pearce, A., Taylor-Robinson, D.C., Williams, H.   +4 more
core   +1 more source

A Case for Anti‐IgE Vaccination

Allergy, EarlyView.
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff, Zahra Gharailoo, Monique Vogel, Martin F. Bachmann   +3 more
wiley   +1 more source

Allergic disorders: A model for establishing how to prevent commondisease

Allergology International, 2004
Allergy to common agents, such as plant pollens, dust mites and foods, is termed atopy. Atopy is the principal cause of the chronic inflammatory diseases of eczema (the skin), hayfever (the nose) and asthma (the lungs) in children and young adults. Atopy
Akiko Yamasaki, Lei Cheng, Sanae Fukuda, Masanobu Chinami, Daisuke Fujita, Danuta Wasserman, Taro Shirakawa   +6 more
doaj   +1 more source

Immune factors preceding diagnosis of glioma: a Prostate Lung Colorectal Ovarian Cancer Screening Trial nested case-control study. [PDF]

, 2019
BackgroundEpidemiological studies of adult glioma have identified genetic and environmental risk factors, but much remains unclear. The aim of the current study was to evaluate anthropometric, disease-related, and prediagnostic immune-related factors for
Bracci, Paige M, Gauderman, W James, Hansen, Helen M, Mccoy, Lucie, Muskens, Ivo S, Wiemels, Joseph L, Wiencke, John K, Wrensch, Margaret R, Zhou, Mi   +8 more
core  

Challenges in interpreting allergen microarrays in relation to clinical symptoms: a machine learning approach. [PDF]

, 2013
Identifying different patterns of allergens and understanding their predictive ability in relation to asthma and other allergic diseases is crucial for the design of personalized diagnostic tools.Allergen-IgE screening using ImmunoCAP ISAC(®) assay was ...
Altmann, Beeh, Bolstad, Breiman, Burrows, Crapo, Custovic, Fayyad, Friedman, Gent, Huber, Knop, Marinho, Melioli, Millán, Murthy, Patelis, Semic-Jusufagic, Simpson, Simpson, Sordillo, Taylor, Wang   +22 more
core   +1 more source

A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS)

BMC Medical Genetics, 2009
Background Asthma and atopy are complex phenotypes with shared genetic component. In this study we attempt to identify genes related to these traits performing a two-stage DNA pooling genome-wide analysis in order to reduce costs.
Kogevinas Manolis, Ramon González Juan, Bustamante Mariona, Castro-Giner Francesc, Jarvis Deborah, Heinrich Joachim, Antó Josep-Maria, Wjst Matthias, Estivill Xavier, de Cid Rafael   +9 more
doaj   +1 more source

Debates in allergy medicine: Specific immunotherapy in children with atopic dermatitis, the "con" view. [PDF]

, 2016
Atopic dermatitis (AD) is a common chronic skin condition in children that has a proven association with other atopic conditions and allergies. These associations, like the general pathophysiology of AD, are complex and not fully understood.
Eichenfield, Lawrence F, Ginsberg, David N   +1 more
core   +3 more sources

Early Epidemiologic and Immune Predictors of Atopic Dermatitis: Reduced Cord Blood Regulatory B10 Cells in the Munich Atopy Prediction Study (MAPS)

Allergy, EarlyView.
In this prospective birth cohort from Munich, comprehensive clinical assessments and longitudinal lifestyle questionnaires were combined with cord blood immune profiling. Infants who later developed AD showed altered cord blood immune signatures, including reduced CD4+ T cells, increased B cells and markedly decreased Breg cells. Epidemiologic factors,
S. Preis, S. Kaesler, M. Koeberle, M. Hils, B. Evers, R. L. Silva, Y. Skabytska, L. Schellenberger, H. Hufnagel, M. Schielein, B. Kuschel, Y. Amar, A. Zink, T. Biedermann, Z. Kurgyis   +14 more
wiley   +1 more source