ABSTRACT Background Atopic dermatitis (AD) significantly impacts quality of life, with well‐documented physical and psychological consequences. While disease burden is well characterised, the influence of psychosocial determinants on AD outcomes remains underexplored. This study examines these factors in an Australian paediatric population.
Ashling Courtney+5 more
wiley +1 more source
Laboratorial atopy markers in children with human immunodeficiency virus
Changes in immune system functions are one of the most important consequences of human immunodeficiency virus (HIV) infection. Studies have reported a higher prevalence of disease mediated by immunological hypersensitivity mechanisms in HIV-positive ...
Cristina Rodrigues Cruz+5 more
doaj +1 more source
Allergic diseases attributable to atopy in a population sample of Asian children
The proportion of allergic diseases attributable to atopy remains a subject of controversy. This study aimed to estimate the population risk of physician-diagnosed asthma, rhinitis and eczema attributed to atopy among a population sample of Asian school ...
Chao-Yi Wu+10 more
doaj +1 more source
Prenatal exposure to TCDD and atopic conditions in the Seveso second generation: a prospective cohort study. [PDF]
Background2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a toxic environmental contaminant that can bioaccumulate in humans, cross the placenta, and cause immunological effects in children, including altering their risk of developing allergies. On July 10,
Brambilla, Paolo+4 more
core +2 more sources
Abbreviations: BLOC1S1, biogenesis of lysosome organelles complex 1 subunit 1; cGAS, cyclic GMP‐AMP synthase; GATA3, GATA binding protein 3; IgE, immunoglobulin E; IKK, inhibitor of nuclear factor kappa‐B kinase; IL, interleukin; mtDNA, mitochondrial DNA; NF‐κB, nuclear factor‐kappa B; OVA, ovalbumin; MC903, vitamin D3 analog; STING, stimulator of ...
Rahul Sharma+8 more
wiley +1 more source
Environmental Exposure to Endotoxin and Decreased Risk of Childhood Atopy
The hygiene hypothesis implies, in immunological terms, that microbial stimulation in early life skews the immune system towards the development of a T helper type 1 (Th1)-type lymphocyte population, and away from a T helper type 2 (Th2)-type development
Tatsuo Sakamoto+5 more
doaj +1 more source
Experiences of Stress among Mothers of Preschoolers with Atopic Dermatitis [PDF]
Purpose: The purpose of this study was to explore and describe the meaning and essence of experiences of stress in mothers of preschoolers with atopic dermatitis. Methods: This study employed a qualitative research design.
Hwayoung Kwen, SungRae Shin
doaj +1 more source
Long-term effects of allergen sensitization and exposure in adult asthma: a prospective study. [PDF]
BACKGROUND: : We investigated the effects of sensitization and exposure to common domestic allergens on longitudinal changes in lung function and bronchial hyperresponsiveness. METHODS: : Subjects attended 2 visits that were 4 years apart.
Adnan Custovic+30 more
core +1 more source
TSLP Expression: Cellular Sources, Triggers, and Regulatory Mechanisms
Thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine initially identified in the culture supernatant of a thymic stromal cell line. Highly expressed in the epidermis in skin lesions of atopic dermatitis patients, TSLP was subsequently found to be
Toshiro Takai
doaj +1 more source
Differences in both prevalence and titre of specific immunoglobulin E among children with asthma in affluent and poor communities within a large town in Ghana. [PDF]
Background Reports from several African countries have noted an increasing prevalence of asthma in areas of extensive urbanization. Objective To investigate the relevance of allergen-specific sensitization and body mass index (BMI) to asthma/wheezing and
Addo-Yobo, E+6 more
core +1 more source