Results 101 to 110 of about 79,824 (366)

Association of early viral lower respiratory infections and subsequent development of atopy, a systematic review and meta-analysis of cohort studies.

PLoS ONE, 2020
IntroductionExisting evidence on the relationship between childhood lower respiratory tract infections (LRTI) and the subsequent atopy development is controversial. We aimed to investigate an association between viral LRTI at 2 years.MethodsWe conducted
Sebastien Kenmoe, Cyprien Kengne-Nde, Abdou Fatawou Modiyinji, Jean Joel Bigna, Richard Njouom   +4 more
doaj   +1 more source

Rhinitis in general practice [PDF]

, 2007
A 3 year old boy presented with a 3 week history of nasal obstruction, clear rhinorrhea, difficulty with feeding and a productive cough. Child was afebrile, had occasional watery itchy eyes and mother claimed that at night he tended to wake up a couple ...
drkvassallo@yahoo.co.uk, Vassallo, Kenneth   +1 more
core  

Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy

Thorax, 2014
Background Airway epithelial cells (AEC) from patients with asthma, appear to have an impaired interferon (IFN)-β and -λ response to infection with rhinovirus.
Kirsten M. Spann, E. Baturcam, J. Schagen, Carmen M. Jones, Claire P Straub, F. M. Preston, Linping Chen, S. Phipps, Peter D. Sly, E. Fantino   +9 more
semanticscholar   +1 more source

Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development

Clinical and Developmental Immunology, 2012
Asthma is a hereditary disease associated with IgE-mediated reaction. Whether maternal atopy and paternal atopy have different impacts on perinatal IgE production and asthma development remains unclear.
Chih-Chiang Wu, Rong-Fu Chen, Ho-Chang Kuo   +2 more
doaj   +1 more source

Allergic disorders: A model for establishing how to prevent commondisease

Allergology International, 2004
Allergy to common agents, such as plant pollens, dust mites and foods, is termed atopy. Atopy is the principal cause of the chronic inflammatory diseases of eczema (the skin), hayfever (the nose) and asthma (the lungs) in children and young adults. Atopy
Akiko Yamasaki, Lei Cheng, Sanae Fukuda, Masanobu Chinami, Daisuke Fujita, Danuta Wasserman, Taro Shirakawa   +6 more
doaj   +1 more source

Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population [PDF]

, 2019
Various phenotypes exist in asthma and Chronic Obstructive Pulmonary Disease (COPD). These are important to identify in order to guide treatment decisions.
Brusselle, Guy, De Buyzere, Marc, Lahousse, Lies, Rietzschel, Ernst, Wijnant, Sara   +4 more
core   +1 more source

Direct Single‐Dose Drug‐Provocation Test Is Safe for Delabelling Penicillin Low‐Risk Reactions in Adults

Allergy, EarlyView.
We show that direct single‐dose provocation test was both safe and effective in delabeling penicillin allergy in low‐risk adult patients, including those with mild delayed skin reactions and those with unknown reactions, such as childhood labels and past syncope episodes. In those who react in the drug provocation test, a T‐cell mechanism was confirmed
Marina Labella, Julia Rodriguez de Guzmán, Patricia Diez‐Echave, María Salas, Rubén Fernández‐Santamaría, Cristobalina Mayorga, Inmaculada Doña, María José Torres   +7 more
wiley   +1 more source

A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS)

BMC Medical Genetics, 2009
Background Asthma and atopy are complex phenotypes with shared genetic component. In this study we attempt to identify genes related to these traits performing a two-stage DNA pooling genome-wide analysis in order to reduce costs.
Kogevinas Manolis, Ramon González Juan, Bustamante Mariona, Castro-Giner Francesc, Jarvis Deborah, Heinrich Joachim, Antó Josep-Maria, Wjst Matthias, Estivill Xavier, de Cid Rafael   +9 more
doaj   +1 more source

Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils [PDF]

, 2017
INTRODUCTION: Asthma with adult onset and elevated blood eosinophils is a difficult-to-treat subgroup. This post hoc analysis evaluated reslizumab, an anti-interleukin-5 monoclonal antibody, in patients with late-onset eosinophilic asthma.
Brusselle, Guy, Germinaro, Matthew, Weiss, Sivan, Zangrilli, James   +3 more
core   +2 more sources

Comprehensive αβ T‐Cell Receptor Repertoire Analysis Reveals a Unique CD8+ TCR Landscape in DOCK8‐Deficient Patients

Allergy, EarlyView.
T cell receptor repertoire analysis by high‐throughput immune repertoire RNA‐sequencing in the patients with DOCK8 deficiency. Comprehensive comparisons revealed a restricted TCR repertoire diversity in the patients. Additional assessments showed potential auto‐reactive CD8+ T cell clones in the patients.Abbreviations: DOCK8, dedicator of cytokinesis ...
Ceren Bozkurt, Gökhan Cildir, Umran Aba, Rahmi Kutay Erdogan, Nicholas I Warnock I, Chung Hoow Kok, Asena Pinar Sefer, Sule Haskologlu, Sidem Didar Tekeoglu, Gülşah Merve Kılınç, Canberk Ipsir, Tugba Arikoglu, Aylin Kont Ozhan, Saliha Esenboga, Ahmet Özen, Elif Karakoç‐Aydiner, Sevgi Bilgiç Eltan, Çigdem Aydogmus, Candan Islamoglu, Kübra Baskın, Betul Karaatmaca, Ayse Metin, Deniz Çagdaş, Figen Dogu, Aydan Ikinciogullari, Safa Baris, Baran Erman   +26 more
wiley   +1 more source