Results 101 to 110 of about 65,128 (311)
Allergy, EarlyView.In this two‐phase study, school‐aged children were classified as at risk or no‐risk based on severe attacks during one‐year follow‐up. Four types of prediction models were developed. Salivary bacteria and serum inflammatory markers, while informative alone, complement past asthma attacks in predicting future attack risk.
Shahriyar Shahbazi Khamas +59 more
wiley +1 more source
Allergy, EarlyView.This study analyzed data from a sub‐cohort of the MEDALLION study to examine the association between maternal adherence to the Mediterranean diet and the development of food allergy in offspring. Maternal dietary intake during pregnancy and lactation was assessed using the validated MedDiet Score, together with individual food group consumption ...
Emilia Vassilopoulou +11 more
wiley +1 more source
Allosteric inhibition of IgE–FcεRI interactions by simultaneous targeting of IgE F(ab’)2 epitopes
Communications BiologyImmunoglobulin E (IgE) plays pivotal roles in allergic diseases through interaction with a high-affinity receptor (FcεRI). We established that Fab fragments of anti-IgE antibodies (HMK-12 Fab) rapidly dissociate preformed IgE-FcεRI complexes in a ...
Takao Hirano +6 more
doaj +1 more source
Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice
Allergy, EarlyView.Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek +7 more
wiley +1 more source
The Nasal Microbiome and Associations With Environmental Exposures and Respiratory Health
Allergy, EarlyView.This study evaluates the association of the nasal microbiome with air pollutants, meteorological conditions, and respiratory health in adolescents. Bacterial diversity is positively associated with hay fever and short‐term NO2 exposure, and negatively with temperature. A Moraxella‐dominated nasotype is linked to lower O3 exposure and higher temperature
Javier Perez‐Garcia +11 more
wiley +1 more source
Atopy and related clinical symptoms among Swiss medical students from 2007 to 2015
Allergy, Asthma & Clinical Immunology, 2018 Background Atopic allergy is a widespread disease with increasing prevalence in the second half of the twentieth century and is most often associated with clinical symptoms, like rhinoconjunctivitis, asthma or eczema.
Lukas Steinegger +4 more
doaj +1 more source
Selective development of a strong Th2 cytokine profile in high‐risk children who develop atopy: risk factors and regulatory role of IFN‐γ, IL‐4 and IL‐10 [PDF]
, 2001 Vincent H. J. van der Velden +5 more
openalex +1 more source
Mediation of Polygenic Asthma Risk Through Gene Expression
Allergy, EarlyView.We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan +29 more
wiley +1 more source
Effects of atopy and rhinitis on exhaled nitric oxide values - a systematic review
Clinical and Translational Allergy, 2011 Background Atopy and rhinitis are among the factors affecting exhaled nitric oxide (FeNO) values and may contribute to difficulties in the clinical interpretation of FeNO measurements.
Linhares Daniela +3 more
doaj +1 more source