Results 171 to 180 of about 65,128 (311)

Predictors of Response to Biologics for Severe Asthma: A Systematic Review and Meta‐Analysis

Allergy, Volume 81, Issue 1, Page 24-55, January 2026.
ABSTRACT Biologics are effective for severe asthma, but not all patients benefit equally. There is an urgent need to understand which biologic works best for which patient. We systematically searched for predictors of response to biologics (except omalizumab) for severe asthma in four bibliographic databases and two trial registries from 1990 to 2024 ...
Anna Rattu, Piers Dixey, David Charles, Chris Brightling, Kian Fan Chung, Apostolos Bossios, Arnaud Bourdin, Ratko Djukanovic, Sven‐Erik Dahlén, Louise Fleming, Rekha Chaudhuri, Erik Melén, Antoine Deschildre, Charles Pilette, Gerard H. Koppelman, Andrew Exley, Freja Anckers, Sarah Miller, Hanna Nielsen, Clare Williams, Ekaterina Khaleva, Graham Roberts, on behalf of the 3TR consortium Respiratory Work Package   +22 more
wiley   +1 more source

Investigating the health economic burden of atopic disease in children from the EAT-On Study. [PDF]

Pediatr Allergy Immunol
Foong RX, Craven J, Du Toit G, Brough HA, Santos AF, Lack G, Sach TH.   +6 more
europepmc   +1 more source

Prevalence of atopy, eosinophilia, and IgE elevation in IgG4-related disease

, 2013
Emanuel Della‐Torre, Hamid Mattoo, Vinay S. Mahajan, Mollie N. Carruthers, Shiv Pillai, John H. Stone   +5 more
openalex   +1 more source

Immune Training of the Interleukin 6 Gene in Airway Epithelial Cells is Central to Asthma Exacerbations

Allergy, Volume 81, Issue 1, Page 157-169, January 2026.
This study aims to investigate how immune activation influences the epigenetic regulation and expression of the Interleukin‐6 (IL‐6) gene during asthma exacerbations. By examining molecular mechanisms of immune training, we seek to elucidate how IL‐6‐driven inflammatory pathways contribute to airway dysfunction and worsening asthma symptoms.
Lars P. Lunding, Markus Weckmann, Ulrich M. Zissler, Constanze Jakwerth, Rebecca Bodenstein‐Sgró, Sina Webering, Christina Vock, Johanna C. Ehlers, Romina A. M. Fernandez Ceballos, Sai Sneha Priya Nemani, Karosham Diren Reddy, Brian George G. Oliver, Cornelis J. Vermeulen, Maarten van de Berge, Carole Ober, Axel Künstner, Hauke Busch, Inke König, Christoph Garbers, Carsten B. Schmidt‐Weber, Marcel F. Nold, Ali Önder Yildirim, Claudia A. Nold‐Petry, Zane Orinska, Thomas Bahmer, Jan Heyckendorf, Gesine Hansen, Erika von Mutius, Klaus F. Rabe, Anna‐Maria Dittrich, Bianca Schaub, Folke Brinkmann, Matthias V. Kopp, Michael Wegmann, The ALLIANCE Study Group as part of the German Centre for Lung Research (DZL)   +34 more
wiley   +1 more source

Parental asthma and risk of offspring asthma from childhood to adolescence: a population-based cohort study. [PDF]

BMJ Open Respir Res
Rørholt Grefslie M, Håberg SE, Magnus MC, Omsland TK, Magnus P.   +4 more
europepmc   +1 more source

Dietary N-3 polyunsaturated fatty acid (PUFA) supplementation during pregnancy is associated with changes in cord blood (CB) progenitor numbers and responsiveness to IL-5 in infants at risk of atopy

, 2003
Holly M Hatfield, Janet A. Dunstan, Lisa Hayes, Roma Sehmi, P. Holt, Judah A. Denburg, Susan L. Prescott   +6 more
openalex   +1 more source

Mouse Allergen Exposure, Wheeze, and Atopy in the First Seven Years of Life [PDF]

, 2006
Wanda Phipatanakul, Juan C. Celedón, Clare D. Ramsey, Diane Sredl, Scott T. Weiss, Diane R. Gold   +5 more
openalex   +1 more source

Cluster Analysis to Identify Distinct Asthma Phenotypes in the ATLANTIS Cohort

Allergy, Volume 81, Issue 1, Page 185-196, January 2026.
This study identified four clinically distinct asthma clusters. The most severe cluster was characterized by type 2 inflammation and exhibited both large and small airways obstruction, as well as air trapping on CT. Patients in the earlier‐onset cluster exhibited more severe bronchial hyperresponsiveness despite a relatively preserved lung function ...
Pauline J. M. Kuks, Tatiana Karp, Jorine E. Hartman, Monica Kraft, Salman Siddiqui, Leonardo M. Fabbri, Bianca Beghé, Klaus F. Rabe, Alberto Papi, Christopher E. Brightling, Dave Singh, Xingnan Li, Janwillem W. H. Kocks, Ulrica Scaffidi‐Argentina, Huib A. M. Kerstjens, Irene H. Heijink, Simon D. Pouwels, Dirk‐Jan Slebos, Maarten van den Berge   +18 more
wiley   +1 more source

Host Immunogenetics and Chronic HCV Infection Shape Atopic Risk in Pediatric Beta-Thalassemia: A Genotype-Phenotype Study. [PDF]

Genes (Basel)
Cuppari C, Mancuso A, Colavita L, Cusmano C, Tallarico V, Caruso V, Chimenz R, Caloiero M, Calafiore M, La Mazza A, Rigoli L.   +10 more
europepmc   +1 more source

81 Dose Response Relationship Between Ascaris Sensitisation and Atopy and Bronchial Hyper-Responsiveness but not Allergic Diseases in Black South Africans

, 2012
Michael Levin, Rudzani Muloiwah, Peter N. Le Souëf, Cassim Motalah   +3 more
openalex   +1 more source