Results 71 to 80 of about 79,824 (366)

DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection

Genome Medicine, 2015
BackgroundThe prevalence of allergic diseases are increasing worldwide, emphasizing the need to elucidate their pathogeneses. The aims of this study were to use a two-stage design to identify DNA methylation levels at cytosine–phosphate–guanine (CpG ...
T. Everson, G. Lyons, Hongmei Zhang, Nelís Soto-Ramírez, G. Lockett, V. Patil, S. Merid, Cilla Sӧderhӓll, Erik Melén, J. Holloway, S. Arshad, W. Karmaus   +11 more
semanticscholar   +1 more source

Allergic Rhinitis—Underrepresented Populations and Barriers to Healthcare Access

The Laryngoscope, EarlyView.
ABSTRACT Objective To establish the prevalence of allergic rhinitis (AR), categorized by demographics and barriers to healthcare, and the prevalence of antihistamine and nasal steroid use in these subgroups. Methods We performed a retrospective, cross‐sectional study utilizing the All of Us Database.
Sophia J. Peifer, Zachary M. Helmen, Stuart Duffield, Chloe Shields, Shray Mehra, David K. Lerner, Shekhar K. Gadkaree   +6 more
wiley   +1 more source

Do early-life exposures explain why more advantaged children get eczema? Findings from the U.K. Millennium Cohort Study [PDF]

, 2015
Background: Atopic dermatitis (eczema) in childhood is socially patterned, with higher incidence in more advantaged populations. However, it is unclear what factors explain the social differences.
Hope, S., Law, C., Pearce, A., Taylor-Robinson, D.C., Williams, H.   +4 more
core   +1 more source

Molecular mechanisms of atopy [PDF]

Mediators of Inflammation, 2001
Production of specific immunoglobulin (Ig)E is the characteristic abnormality of atopy. IgE is produced by B lymphocytes under the influence of interleukin (IL)4 and IL-13. IgE binds to high-affinity IgE receptors (Fc«RI) on mast cells to induce degranulation and mediator synthesis.
openaire   +4 more sources

Sinonasal Intervention Reduces the Need for Pressure Equalization Tube Placement in Atopic Adults

The Laryngoscope, EarlyView.
Surgical and medical management of atopic sinonasal diseases decreases the risk of middle ear disease and the subsequent need for pressure equalization tubes. ABSTRACT Objectives To determine the impact of management of upper airway atopic disease on middle ear and eustachian tube function in adults.
Lawrance Lee, Mihai A. Bentan, Elizabeth Mastoloni, Theodore A. Schuman   +3 more
wiley   +1 more source

Impact of atopic dermatitis on renal dysfunction: insights from patient data and animal models

Frontiers in Immunology
IntroductionAtopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritus, immune dysregulation, and compromised skin barrier function.
Arisa Ikeda, Arisa Ikeda, Ge Peng, Wanchen Zhao, Alafate Abudouwanli, Shigaku Ikeda, Shigaku Ikeda, François Niyonsaba, François Niyonsaba, Yusuke Suzuki   +9 more
doaj   +1 more source

Factors Affecting Nasal Discharge in Chronic Rhinosinusitis Patients

The Laryngoscope, EarlyView.
This study aimed to identify patient‐specific factors influencing the severity of nasal drainage in chronic rhinosinusitis (CRS) patients. It found that postnasal discharge (PND) was the most severe symptom, with female gender, CRS without nasal polyps, prior endoscopic sinus surgery, and allergies significantly associated with severe PND.
Pranav A. Patel, Ethan M. Kallenberger, Shaun A. Nguyen, Jess C. Mace, Alexander N. Duffy, Zachary M. Soler, Timothy L. Smith, Rodney J. Schlosser   +7 more
wiley   +1 more source

Bacterial Exposures and Associations with Atopy and Asthma in Children

PLoS ONE, 2015
Background The increase in prevalence of asthma and atopic diseases in Western countries has been linked to aspects of microbial exposure patterns of people. It remains unclear which microbial aspects contribute to the protective farm effect.
M. Valkonen, I. Wouters, M. Täubel, H. Rintala, V. Lenters, R. Vasara, J. Genuneit, C. Braun‐Fahrländer, R. Piarroux, E. von Mutius, D. Heederik, A. Hyvärinen   +11 more
semanticscholar   +1 more source

Guideline for the diagnosis, treatment, and prevention of respiratory syncytial virus infection in children in China

Pediatric Investigation, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is one of the most common respiratory pathogens in children under 5 years of age worldwide and it seriously threatens children's health. In recent years, great progress has been made in the field of RSV‐related diseases.
Committee of Pediatrics, China Medical Education Association, Subspecialty Group of Respiratory Diseases, Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of China Non‐public Medical Institution Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China Medical News and Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, Global Pediatric Respiratory Alliance, Beijing Hairun Charity Foundation   +16 more
wiley   +1 more source

High body mass index is not associated with atopy in schoolchildren living in rural and urban areas of Ghana

BMC Public Health, 2011
Background Factors which determine the development of atopy and the observed rural-urban gradient in its prevalence are not fully understood. High body mass index (BMI) has been associated with asthma and potentially atopy in industrialized countries. In
Obeng Benedicta B, Amoah Abena S, Klipstein-Grobusch Kerstin, Larbi Irene A, Wilson Michael D, Yazdanbakhsh Maria, Boakye Daniel A   +6 more
doaj   +1 more source