Results 81 to 90 of about 3,968 (254)
Predictors of Response to Biologics for Severe Asthma: A Systematic Review and Meta‐Analysis
ABSTRACT Biologics are effective for severe asthma, but not all patients benefit equally. There is an urgent need to understand which biologic works best for which patient. We systematically searched for predictors of response to biologics (except omalizumab) for severe asthma in four bibliographic databases and two trial registries from 1990 to 2024 ...
Anna Rattu +22 more
wiley +1 more source
This study aims to investigate how immune activation influences the epigenetic regulation and expression of the Interleukin‐6 (IL‐6) gene during asthma exacerbations. By examining molecular mechanisms of immune training, we seek to elucidate how IL‐6‐driven inflammatory pathways contribute to airway dysfunction and worsening asthma symptoms.
Lars P. Lunding +34 more
wiley +1 more source
Eosinophilic gastroenteritis with refractory ulcer disease and gastrointestinal bleeding as a rare manifestation of seronegative gastrointestinal food allergy [PDF]
Gastrointestinal bleeding and iron deficiency anaemia may cause severe symptoms and may require extensive diagnostics and substantial amounts of health resources.
Alexander F Hagel +7 more
core +2 more sources
Atopie-Patch-Test: Reaktionsindex und Tertiärprävention [PDF]
Ein Epikutantest mit Allergenen, die IgE-vermittelte Reaktionen auslösen können, und die Evaluation ekzematöser Hautreaktionen nach 48-72h wird Atopie-Patch-Test (APT) genannt. Diese Arbeit untersucht den APT unter „real life“-Bedingungen an einem Kollektiv von 449 Patienten auf verschiedene Parameter.
openaire
Cluster Analysis to Identify Distinct Asthma Phenotypes in the ATLANTIS Cohort
This study identified four clinically distinct asthma clusters. The most severe cluster was characterized by type 2 inflammation and exhibited both large and small airways obstruction, as well as air trapping on CT. Patients in the earlier‐onset cluster exhibited more severe bronchial hyperresponsiveness despite a relatively preserved lung function ...
Pauline J. M. Kuks +18 more
wiley +1 more source
Orofacial Granulomatosis [PDF]
Orofacial granulomatosis (OFG) is an uncommon chronic inflammatory disorder of the orofacial region. It is characterized by subepithelial noncaseating granulomas and has a spectrum of possible clinical manifestations ranging from subtle oral mucosal ...
Al-Hamad, A, Fedele, S, Porter, S
core +1 more source
Our study reveals Aboriginal and Torres Strait Islander people have a high allergy burden, with asthma the most prevalent; yet they remain under‐represented in research. ABSTRACT Allergic diseases and asthma are significant public health concerns in Australia and globally.
Desalegn Markos Shifti +9 more
wiley +1 more source
Evaluation of the atopy patch test and the cutaneous late-phase reaction as relevant models for the study of allergic inflammation in patients with atopic eczema [PDF]
Elisabeth G. Langeveld-Wildschut +6 more
openalex +1 more source
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Axel De Greef +6 more
wiley +1 more source
ABSTRACT Background Paediatric airway diseases such as asthma, allergies, rhinitis, upper respiratory tract infections and acute otitis media are major health challenges for children globally. The prevalence of these conditions has been increasing, impacting children's quality of life, educational attainment and imposing a substantial economic burden ...
Cecilia Rosso +7 more
wiley +1 more source

