Results 111 to 120 of about 1,060 (168)
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Journal of Pharmaceutical and Biomedical Analysis, 2020
Consulting the national pharmacopoeia, no official quality standard was found for estimation of related substances and assay of atosiban acetate injection, of which main active component is atosiban. To solve this problem, herein, a novel high performance liquid chromatographic (HPLC) method was developed and validated in this study.
Jinhui Wu, Yiqiao Hu
exaly +3 more sources
Consulting the national pharmacopoeia, no official quality standard was found for estimation of related substances and assay of atosiban acetate injection, of which main active component is atosiban. To solve this problem, herein, a novel high performance liquid chromatographic (HPLC) method was developed and validated in this study.
Jinhui Wu, Yiqiao Hu
exaly +3 more sources
Atosiban and nifedipine in acute tocolysis: A comparative study
European Journal of Obstetrics, Gynecology and Reproductive Biology, 2006The objective was to compare the effectiveness, efficacy, and safety of atosiban and nifedipine in preventing or delaying premature labor.An interventional, randomized, controlled trial of 63 women experiencing preterm labor varying from 24 to 35 completed weeks of gestation.
Wafa R, Al-Omari +3 more
exaly +3 more sources
Atosiban and nifedipin for the treatment of preterm labor
International Journal of Gynecology and Obstetrics, 2005AbstractObjectiveTo perform a comparison between atosiban (oxytocin antagonist) and nifedipin (calcium channel blocker) for acute treatment of preterm labor and their maternal safety. Methods: A randomized controlled trial study was performed on 80 pregnant women with preterm labor, between 26 and 34 weeks of pregnancy, in Akbar Abadi Teaching Hospital
Maryam Kashanian
exaly +3 more sources
Treatment of Preterm Labor with the Oxytocin Antagonist Atosiban
American Journal of Perinatology, 1996The purpose of this study was to describe the course of preterm labor in patients receiving a standard intravenous infusion of the oxytocin antagonist atosiban. An open-labeled, non-randomized study was conducted at 4 sites. Successful tocolysis was defined as delay of delivery larger than 48 hours from starting atosiban and no need for an alternate ...
T Murphy Goodwin
exaly +3 more sources
The use of atosiban and ritodrine in external cephalic version
Acta Obstetricia Et Gynecologica Scandinavica, 2007AbstractObjective. To compare the efficacy of atosiban and ritodrine as tocolytic agents for successful external cephalic version (ECV). Factors affecting the success of ECV, as well as maternal and perinatal outcomes are reviewed. Method. A retrospective review of women who underwent ECV with either atosiban (2004) or ritodrine (2002).
Iosifina, Stergiotou +2 more
exaly +3 more sources
Drugs, 2004
Oxytocin antagonists are synthetic analogues that have the nonapeptide structure of oxytocin. They act by competing with oxytocin for receptors in the myometrium. Animal experiments and pilot clinical studies have examined several agents and, of these, atosiban has been the object of extensive clinical trials.
Vassilis, Tsatsaris +2 more
openaire +2 more sources
Oxytocin antagonists are synthetic analogues that have the nonapeptide structure of oxytocin. They act by competing with oxytocin for receptors in the myometrium. Animal experiments and pilot clinical studies have examined several agents and, of these, atosiban has been the object of extensive clinical trials.
Vassilis, Tsatsaris +2 more
openaire +2 more sources
Clinical Obstetrics and Gynecology, 1995
The role of oxytocin and oxytocin receptors in preterm labor is perhaps more prominent than once thought. The blockade of oxytocin and/or oxytocin receptors has both a theoretical and clinical aspect. Initial trials with the oxytocin antagonist atosiban have been encouraging with respect to efficacy and side effect profile. Current trials are examining
openaire +2 more sources
The role of oxytocin and oxytocin receptors in preterm labor is perhaps more prominent than once thought. The blockade of oxytocin and/or oxytocin receptors has both a theoretical and clinical aspect. Initial trials with the oxytocin antagonist atosiban have been encouraging with respect to efficacy and side effect profile. Current trials are examining
openaire +2 more sources
Placental passage of the oxytocin antagonist atosiban
American Journal of Obstetrics and Gynecology, 1995We wanted to determine the degree of placental transfer of atosiban (Antocin), an oxytocin antagonist, in pregnant women at term. We also assessed the effects of the infusion on umbilical cord blood gases at birth and the maternal hematocrit drop after cesarean section.Eight women undergoing elective cesarean section at term were studied. Each received
G J, Valenzuela +3 more
openaire +2 more sources
Molecular Modeling of the Neurohypophyseal Receptor/Atosiban Complexes
Protein & Peptide Letters, 2003The neurohypophyseal nonapeptide hormone oxytocin (OT) is the strongest uterotonic substance known and is responsible for the initiation of labor. Conversely, oxytocin antagonists blocking uterine OT receptor can suppress uterus contraction. In this paper we describe a computer simulated docking pertinent to affinity of an oxytocin antagonist atosiban ...
Magdalena Ślusarz +5 more
openaire +2 more sources