Results 1 to 10 of about 1,587 (161)

The Oxytocin-Oxytocin Receptor System and Its Antagonists as Tocolytic Agents [PDF]

International Journal of Endocrinology, 2011
Oxytocin, a hormone involved in numerous physiologic processes, plays a central role in the mechanisms of parturition and lactation. It acts through its receptor, which belongs to the G-protein-coupled receptor superfamily, while Gq/phospholipase C (PLC)/
Nikolaos Vrachnis, Fotodotis M. Malamas, Stavros Sifakis, Efthymios Deligeoroglou, Zoe Iliodromiti   +4 more
doaj   +7 more sources

Combination of tocolytic agents for inhibiting preterm labour [PDF]

The Cochrane Library, 2014
Preterm birth represents the single largest cause of mortality and morbidity for newborns and a major cause of morbidity for pregnant women. Tocolytic agents include a wide range of drugs that can inhibit labour to prolong pregnancy. This may gain time to allow the fetus to mature further before being born, permit antenatal corticosteroid ...
Joshua Vogel, Olufemi Oladapo, Thérèse Dowswell   +2 more
exaly   +4 more sources

Tocolytic agents and the failure to improve neonatal outcomes

Pregnancy
Premature delivery has long been a major problem in obstetrics. Increased perinatal morbidity and mortality as well as substantial health care costs, both short and long term, have driven the efforts to combat this complication.
Jack FitzSimmons, Emily Oliver
doaj   +3 more sources

Noninvasive positive-pressure ventilation in pregnancy to treat acute pulmonary edema induced by tocolytic agents: a case report [PDF]

Journal of Medical Case Reports, 2021
Background We report a case of pulmonary edema induced by tocolytic agents that was successfully managed with noninvasive positive-pressure ventilation (NPPV) and resulted in extended gestation.
Kotaro Takahashi, Koji Nishijima, Masayuki Yamaguchi, Kensuke Matsumoto, Shunya Sugai, Takayuki Enomoto   +5 more
doaj   +2 more sources

Cost-effectiveness of antenatal corticosteroids and tocolytic agents in the management of preterm birth: A systematic review [PDF]

EClinicalMedicine, 2022
Summary: Background: Preterm birth is a leading cause of neonatal mortality and morbidity, and imposes high health and societal costs. Antenatal corticosteroids (ACS) to accelerate fetal lung maturation are commonly used in conjunction with tocolytics ...
Elizabeth Sebastian, Chloe Bykersma, Alexander Eggleston, Katherine E. Eddy, Sher Ting Chim, Rana Islamiah Zahroh, Nick Scott, Doris Chou, Olufemi T. Oladapo, Joshua P. Vogel   +9 more
doaj   +2 more sources

Comparison of Tocolytic Agents for Successful External Cephalic Version: A Bayesian Network Meta-Analysis of Sixteen Randomized Controlled Trials [PDF]

Balkan Medical Journal
Background: Cesarean section is frequently performed for breech presentation; however, external cephalic version (ECV) is recommended as an alternative strategy to increase the likelihood of vaginal birth.
Yunyun Xiao, Jinhe Shi, Yan Dong, Lu Han
doaj   +2 more sources

Success rate in preterm uterine contraction inhibition with tocolytic agents in a tertiary care center [PDF]

International Journal of Women's Health, 2016
Duangsamorn Kiatsuda, Jadsada Thinkhamrop, Witoon Prasertcharoensuk Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand Objective: This study aims to assess the success rate of inhibiting preterm ...
Kiatsuda D, Thinkhamrop J, Prasertcharoensuk W   +2 more
doaj   +2 more sources

Comparison of terbutaline and atosiban as tocolytic agents in intrauterine repair of myelomeningocele: a retrospective cohort study [PDF]

Brazilian Journal of Anesthesiology
Background: Myelomeningocele (MMC) is a neural tube defect disease. Antenatal repair of fetal MMC is an alternative to postnatal repair. Many agents can be used as tocolytics during the in utero fetal repair such as β2-agonists and oxytocin receptor ...
Shirley Andrade Santos, Fernando Souza Nani, Elaine Imaeda de Moura, Diogo Lima de Carvalho, Guilherme Jorge Mattos Miguel, Cristiane Maria Federicci Haddad, Joaquim Edson Vieira, Victor Bunduki, Mário Henrique Burlacchini de Carvalho, Rossana Pulcineli Vieira Francisco, Daniel Dante Cardeal, Hermann dos Santos Fernandes   +11 more
doaj   +2 more sources

Therapeutic role of nifedipine in threatened preterm labor: Current evidence and future perspectives. [PDF]

Int J Gynaecol Obstet
Abstract Preterm birth occurs in approximately 10% of all pregnancies, and is not only the leading cause of neonatal mortality but also a major contributor to short‐ and long‐term morbidities due to immaturity. Preterm birth has also been linked to an increased risk of maternal cardiovascular and cerebrovascular diseases, making it a critical concern ...
Imatake H, Chigusa Y, Mogami H, Morita S, Mandai M.   +4 more
europepmc   +2 more sources

Effects of sympathomimetic tocolytic agents on the fetus [PDF]

Journal of Perinatal Medicine, 1974
The variety of factors controlling the onset of parturition, as well as the very complex mechanisms which physiologically maintain pregnancy by inhibiting uterine contractions are only partially understood today. As long as the triggering mechanisms, and the conditions favoring timely and early labor are incompletely known, symptomatic therapeutic ...
exaly   +3 more sources